<italic toggle="yes">Toxoplasma</italic> Cathepsin Protease B and Aspartyl Protease 1 Are Dispensable for Endolysosomal Protein Digestion
ABSTRACT The lysosome-like vacuolar compartment (VAC) is a major site of proteolysis in the intracellular parasite Toxoplasma gondii. Previous studies have shown that genetic ablation of a VAC-residing cysteine protease, cathepsin protease L (CPL), resulted in the accumulation of undigested protein...
Enregistré dans:
Auteurs principaux: | Christian McDonald, David Smith, Manlio Di Cristina, Geetha Kannan, Zhicheng Dou, Vern B. Carruthers |
---|---|
Format: | article |
Langue: | EN |
Publié: |
American Society for Microbiology
2020
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/f28ca7b56c8f483ca29aa45225b73bdc |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Role of <italic toggle="yes">Toxoplasma gondii</italic> Chloroquine Resistance Transporter in Bradyzoite Viability and Digestive Vacuole Maintenance
par: Geetha Kannan, et autres
Publié: (2019) -
A <named-content content-type="genus-species">Toxoplasma gondii</named-content> Ortholog of <italic toggle="yes">Plasmodium</italic> GAMA Contributes to Parasite Attachment and Cell Invasion
par: My-Hang Huynh, et autres
Publié: (2016) -
Immune reactivity and host modulatory roles of two novel Haemonchus contortus cathepsin B-like proteases
par: Mariam Bakshi, et autres
Publié: (2021) -
Hindrance of the Proteolytic Activity of Neutrophil-Derived Serine Proteases by Serine Protease Inhibitors as a Management of Cardiovascular Diseases and Chronic Inflammation
par: Timo Burster, et autres
Publié: (2021) -
<named-content content-type="genus-species">Toxoplasma gondii</named-content> LCAT Primarily Contributes to Tachyzoite Egress
par: Aric J. Schultz, et autres
Publié: (2018)