Catalytic enantioselective C(sp 3)–H functionalization involving radical intermediates

Enantioselective functionalization of ubiquitous C(sp3)–H bonds via radical species has witnessed a renaissance in the past years. Here, the authors summarize the main achievements in the field by identifying two main reaction pathways determining the stereochemistry and give an outlook on future ch...

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Auteurs principaux: Chi Zhang, Zhong-Liang Li, Qiang-Shuai Gu, Xin-Yuan Liu
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/f28f20eec4be4ea6b4db528d8daffcbb
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Résumé:Enantioselective functionalization of ubiquitous C(sp3)–H bonds via radical species has witnessed a renaissance in the past years. Here, the authors summarize the main achievements in the field by identifying two main reaction pathways determining the stereochemistry and give an outlook on future challenges and opportunities.