Catalytic enantioselective C(sp 3)–H functionalization involving radical intermediates

Enantioselective functionalization of ubiquitous C(sp3)–H bonds via radical species has witnessed a renaissance in the past years. Here, the authors summarize the main achievements in the field by identifying two main reaction pathways determining the stereochemistry and give an outlook on future ch...

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Bibliographic Details
Main Authors: Chi Zhang, Zhong-Liang Li, Qiang-Shuai Gu, Xin-Yuan Liu
Format: article
Language:EN
Published: Nature Portfolio 2021
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Q
Online Access:https://doaj.org/article/f28f20eec4be4ea6b4db528d8daffcbb
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Summary:Enantioselective functionalization of ubiquitous C(sp3)–H bonds via radical species has witnessed a renaissance in the past years. Here, the authors summarize the main achievements in the field by identifying two main reaction pathways determining the stereochemistry and give an outlook on future challenges and opportunities.