Long-Lasting T Cell-Independent IgG Responses Require MyD88-Mediated Pathways and Are Maintained by High Levels of Virus Persistence
ABSTRACT Many viruses induce acute T cell-independent (TI) B cell responses due to their repetitive epitopes and the induction of innate cytokines. Nevertheless, T cell help is thought necessary for the development of long-lasting antiviral antibody responses in the form of long-lived plasma cells a...
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| Main Authors: | , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2013
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| Subjects: | |
| Online Access: | https://doaj.org/article/f28fde7ad8614dbcb042ef58ed7ea3f4 |
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