MicroRNA-326 impairs chemotherapy resistance in non small cell lung cancer by suppressing histone deacetylase SIRT1-mediated HIF1α and elevating VEGFA: Roles of miR-326 in chemoresistance of NSCLC

Compelling evidence has implicated the role of microRNAs (miRs or miRNAs) in lung cancer. Sirtuin-1 (SIRT1) is key contributor to the progression of non small cell lung cancer (NSCLC). This study was intended to investigate whether miR-326 affected NSCLC associated with SIRT1. miR-326 and SIRT1 expr...

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Auteurs principaux: Jinying Wei, Guangping Meng, Jing Wu, Ying Wang, Qiang Zhang, Ting Dong, Jin Bao, Chunyan Wang, Jie Zhang
Format: article
Langue:EN
Publié: Taylor & Francis Group 2021
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Accès en ligne:https://doaj.org/article/f29034f89fe24d43bf3903b6fe4f6ec8
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