Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP

Natriuretic peptides (NPs) are important hormones that regulate cardiovascular physiology by increasing cGMP levels in cardiomyocytes. Here the authors use scanning ion conductance microscopy and a cGMP FRET sensor to identify a differential localisation pattern for the natriuretic peptide receptors...

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Autores principales: Hariharan Subramanian, Alexander Froese, Peter Jönsson, Hannes Schmidt, Julia Gorelik, Viacheslav O. Nikolaev
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/f29494c168df440eb80c83114574bf1a
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spelling oai:doaj.org-article:f29494c168df440eb80c83114574bf1a2021-12-02T16:49:21ZDistinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP10.1038/s41467-018-04891-52041-1723https://doaj.org/article/f29494c168df440eb80c83114574bf1a2018-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04891-5https://doaj.org/toc/2041-1723Natriuretic peptides (NPs) are important hormones that regulate cardiovascular physiology by increasing cGMP levels in cardiomyocytes. Here the authors use scanning ion conductance microscopy and a cGMP FRET sensor to identify a differential localisation pattern for the natriuretic peptide receptors within the heart.Hariharan SubramanianAlexander FroesePeter JönssonHannes SchmidtJulia GorelikViacheslav O. NikolaevNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Hariharan Subramanian
Alexander Froese
Peter Jönsson
Hannes Schmidt
Julia Gorelik
Viacheslav O. Nikolaev
Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP
description Natriuretic peptides (NPs) are important hormones that regulate cardiovascular physiology by increasing cGMP levels in cardiomyocytes. Here the authors use scanning ion conductance microscopy and a cGMP FRET sensor to identify a differential localisation pattern for the natriuretic peptide receptors within the heart.
format article
author Hariharan Subramanian
Alexander Froese
Peter Jönsson
Hannes Schmidt
Julia Gorelik
Viacheslav O. Nikolaev
author_facet Hariharan Subramanian
Alexander Froese
Peter Jönsson
Hannes Schmidt
Julia Gorelik
Viacheslav O. Nikolaev
author_sort Hariharan Subramanian
title Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP
title_short Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP
title_full Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP
title_fullStr Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP
title_full_unstemmed Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP
title_sort distinct submembrane localisation compartmentalises cardiac npr1 and npr2 signalling to cgmp
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/f29494c168df440eb80c83114574bf1a
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