Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP
Natriuretic peptides (NPs) are important hormones that regulate cardiovascular physiology by increasing cGMP levels in cardiomyocytes. Here the authors use scanning ion conductance microscopy and a cGMP FRET sensor to identify a differential localisation pattern for the natriuretic peptide receptors...
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Nature Portfolio
2018
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oai:doaj.org-article:f29494c168df440eb80c83114574bf1a2021-12-02T16:49:21ZDistinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP10.1038/s41467-018-04891-52041-1723https://doaj.org/article/f29494c168df440eb80c83114574bf1a2018-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04891-5https://doaj.org/toc/2041-1723Natriuretic peptides (NPs) are important hormones that regulate cardiovascular physiology by increasing cGMP levels in cardiomyocytes. Here the authors use scanning ion conductance microscopy and a cGMP FRET sensor to identify a differential localisation pattern for the natriuretic peptide receptors within the heart.Hariharan SubramanianAlexander FroesePeter JönssonHannes SchmidtJulia GorelikViacheslav O. NikolaevNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018) |
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Science Q Hariharan Subramanian Alexander Froese Peter Jönsson Hannes Schmidt Julia Gorelik Viacheslav O. Nikolaev Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP |
description |
Natriuretic peptides (NPs) are important hormones that regulate cardiovascular physiology by increasing cGMP levels in cardiomyocytes. Here the authors use scanning ion conductance microscopy and a cGMP FRET sensor to identify a differential localisation pattern for the natriuretic peptide receptors within the heart. |
format |
article |
author |
Hariharan Subramanian Alexander Froese Peter Jönsson Hannes Schmidt Julia Gorelik Viacheslav O. Nikolaev |
author_facet |
Hariharan Subramanian Alexander Froese Peter Jönsson Hannes Schmidt Julia Gorelik Viacheslav O. Nikolaev |
author_sort |
Hariharan Subramanian |
title |
Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP |
title_short |
Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP |
title_full |
Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP |
title_fullStr |
Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP |
title_full_unstemmed |
Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP |
title_sort |
distinct submembrane localisation compartmentalises cardiac npr1 and npr2 signalling to cgmp |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/f29494c168df440eb80c83114574bf1a |
work_keys_str_mv |
AT hariharansubramanian distinctsubmembranelocalisationcompartmentalisescardiacnpr1andnpr2signallingtocgmp AT alexanderfroese distinctsubmembranelocalisationcompartmentalisescardiacnpr1andnpr2signallingtocgmp AT peterjonsson distinctsubmembranelocalisationcompartmentalisescardiacnpr1andnpr2signallingtocgmp AT hannesschmidt distinctsubmembranelocalisationcompartmentalisescardiacnpr1andnpr2signallingtocgmp AT juliagorelik distinctsubmembranelocalisationcompartmentalisescardiacnpr1andnpr2signallingtocgmp AT viacheslavonikolaev distinctsubmembranelocalisationcompartmentalisescardiacnpr1andnpr2signallingtocgmp |
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1718383372125863936 |