Optimizing Adaptive Therapy Based on the Reachability to Tumor Resistant Subpopulation

Adaptive therapy exploits the self-organization of tumor cells to delay the outgrowth of resistant subpopulations successfully. When the tumor has aggressive resistant subpopulations, the outcome of adaptive therapy was not superior to maximum tolerated dose therapy (MTD). To explore methods to impr...

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Bibliographic Details
Main Authors: Jiali Wang, Yixuan Zhang, Xiaoquan Liu, Haochen Liu
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
Online Access:https://doaj.org/article/f29f0ba5366a444ebd69aa4b72ee743e
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