Ceftazidime/Avibactam-Resistant <i>Klebsiella pneumoniae</i> subsp. <i>pneumoniae</i> Isolates in a Tertiary Italian Hospital: Identification of a New Mutation of the Carbapenemase Type 3 (KPC-3) Gene Conferring Ceftazidime/Avibactam Resistance

Código QR

Ceftazidime/Avibactam-Resistant <i>Klebsiella pneumoniae</i> subsp. <i>pneumoniae</i> Isolates in a Tertiary Italian Hospital: Identification of a New Mutation of the Carbapenemase Type 3 (KPC-3) Gene Conferring Ceftazidime/Avibactam Resistance

Several <i>Klebsiella pneumoniae</i> carpabenemase (KPC) gene mutations are associated with ceftazidime/avibactam (CAZ-AVI) resistance. Here, we describe four <i>Klebsiella pneumoniae</i> subsp. <i>pneumoniae</i> CAZ-AVI-resistant clinical isolates, collected at t...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Carla Fontana, Marco Favaro, Laura Campogiani, Vincenzo Malagnino, Silvia Minelli, Maria Cristina Bossa, Anna Altieri, Massimo Andreoni, Loredana Sarmati
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	ceftazidime/avibactam multi-drug resistance antibiotic resistance beta-lactamase inhibitors resistance Q168L substitution Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/f2a28b6a5c4a4818af77015ad2982ba4
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Suboptimal drug exposure leads to selection of different subpopulations of ceftazidime-avibactam-resistant Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae in a critically ill patient
por: Paolo Gaibani, et al.
Publicado: (2021)

A Ceftazidime-Avibactam-Resistant and Carbapenem-Susceptible <named-content content-type="genus-species">Klebsiella pneumoniae</named-content> Strain Harboring <italic toggle="yes">bla</italic><sub>KPC-14</sub> Isolated in New York City
por: Siqiang Niu, et al.
Publicado: (2020)

In-Vitro Selection of Ceftazidime/Avibactam Resistance in OXA-48-Like-Expressing <i>Klebsiella pneumoniae</i>: In-Vitro and In-Vivo Fitness, Genetic Basis and Activities of β-Lactam Plus Novel β-Lactamase Inhibitor or β-Lactam Enhancer Combinations
por: Snehal Palwe, et al.
Publicado: (2021)

Analyses of a Ceftazidime-Avibactam-Resistant <italic toggle="yes">Citrobacter freundii</italic> Isolate Carrying <italic toggle="yes">bla</italic><sub>KPC-2</sub> Reveals a Heterogenous Population and Reversible Genotype
por: Mariana Castanheira, et al.
Publicado: (2018)

<italic toggle="yes">Klebsiella pneumoniae</italic> Carbapenemase-2 (KPC-2), Substitutions at Ambler Position Asp179, and Resistance to Ceftazidime-Avibactam: Unique Antibiotic-Resistant Phenotypes Emerge from β-Lactamase Protein Engineering
por: Melissa D. Barnes, et al.
Publicado: (2017)

In Vitro Activity Comparison of Ceftazidime–Avibactam and Aztreonam–Avibactam Against Bloodstream Infections With Carbapenem-Resistant Organisms in China
por: Wei Yu, et al.
Publicado: (2021)

OXA-48-Mediated Ceftazidime-Avibactam Resistance Is Associated with Evolutionary Trade-Offs
por: Christopher Fröhlich, et al.
Publicado: (2019)

Dynamic Emergence of Mismatch Repair Deficiency Facilitates Rapid Evolution of Ceftazidime-Avibactam Resistance in <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content> Acute Infection
por: Pavel P. Khil, et al.
Publicado: (2019)

Antimicrobial activities of ceftazidime/avibactam, ceftolozane/tazobactam, imipenem/relebactam, meropenem/vaborbactam, and comparators against Pseudomonas aeruginosa from patients with skin and soft tissue infections
por: Helio S. Sader, et al.
Publicado: (2021)

In vitro activity of ceftazidime-avibactam against Enterobacterales and Pseudomonas aeruginosa isolates collected in Latin America as part of the ATLAS global surveillance program, 2017–2019
por: James A. Karlowsky, et al.
Publicado: (2021)

Treatment of UTIs Due to <i>Klebsiella pneumoniae</i> Carbapenemase-Producers: How to Use New Antibiotic Drugs? A Narrative Review
por: Caroline Chapelle, et al.
Publicado: (2021)

Successful treatment of infective endocarditis due to pandrug-resistant Klebsiella pneumoniae with ceftazidime-avibactam and aztreonam
por: Majed F. Alghoribi, et al.
Publicado: (2021)

Ceftazidime Is the Key Diversification and Selection Driver of VIM-Type Carbapenemases
por: Laura Martínez-García, et al.
Publicado: (2018)

Evaluation of ceftazidime/avibactam alone and in combination with amikacin, colistin and tigecycline against Klebsiella pneumoniae carbapenemase-producing K. pneumoniae by in vitro time-kill experiment.
por: Fangzhou Wang, et al.
Publicado: (2021)

The Monte Carlo Simulation of Three Antimicrobials for Empiric Treatment of Adult Bloodstream Infections With Carbapenem-Resistant Enterobacterales in China
por: Dongna Zou, et al.
Publicado: (2021)

Struggle To Survive: the Choir of Target Alteration, Hydrolyzing Enzyme, and Plasmid Expression as a Novel Aztreonam-Avibactam Resistance Mechanism
por: Ke Ma, et al.
Publicado: (2020)

Prevalence of carbapenemase-producing <i>Klebsiella pneumonia</i> in Gomel Region of Belarus and their sensitivity to antibiotics, antibiotic combinations, and decontaminants
por: D. V. Tapalski, et al.
Publicado: (2020)

Herbicide Resistance in <i>Phalaris</i> Species: A Review
por: Javid Gherekhloo, et al.
Publicado: (2021)

Antimicrobial Activity of a Lipidated Temporin L Analogue against Carbapenemase-Producing <i>Klebsiella pneumoniae</i> Clinical Isolates
por: Emanuela Roscetto, et al.
Publicado: (2021)

<i>Clostridioides difficile</i> and Vancomycin-Resistant Enterococci in COVID-19 Patients with Severe Pneumonia
por: Kateřina Bogdanová, et al.
Publicado: (2021)

Genotype and mutation patterns of macrolide resistance genes of Mycoplasma pneumoniae from children with pneumonia in Qingdao, China, in 2019
por: Fa-Chun Jiang, et al.
Publicado: (2021)

Differences in Germination of ACCase-Resistant Biotypes Containing Isoleucine-1781-Leucine Mutation and Susceptible Biotypes of Wild Oat (<i>Avena sterilis</i> ssp. <i>ludoviciana</i>)
por: Fatemeh Benakashani, et al.
Publicado: (2021)

Bacterial membrane vesicles from Acinetobacter baumannii induced by ceftazidime are more virulent than those induced by imipenem
por: Chun-Hsiang Chiu, et al.
Publicado: (2020)

ANTIBIOTIC RESISTANCE OF KLEBSIELLA PNEUMONIAE TO CEPHALOSPORINS
por: E. V. Anganova, et al.
Publicado: (2017)

Efficacy of Ceftazidime and Cefepime in the Management of COVID-19 Patients: Single Center Report from Egypt
por: Ragaey A. Eid, et al.
Publicado: (2021)

A 3D-Printed Microfluidic Device for qPCR Detection of Macrolide-Resistant Mutations of <i>Mycoplasma pneumoniae</i>
por: Anyan Wang, et al.
Publicado: (2021)

Costo-efectividad de ceftazidima/avibactam versus colistin + meropenem en el tratamiento de infecciones por enterobacterias resistentes a carbapenémicos en Chile
por: Gutiérrez A.,Magda, et al.
Publicado: (2021)

Emergence of a Plasmid-Encoded Resistance-Nodulation-Division Efflux Pump Conferring Resistance to Multiple Drugs, Including Tigecycline, in <named-content content-type="genus-species">Klebsiella pneumoniae</named-content>
por: Luchao Lv, et al.
Publicado: (2020)

Antimicrobial Resistance and Genomic Characterization of Six New Sequence Types in Multidrug-Resistant <i>Pseudomonas aeruginosa</i> Clinical Isolates from Pakistan
por: Sidra Irum, et al.
Publicado: (2021)

Mechanisms of Resistance to Macrolide Antibiotics among <i>Staphylococcus aureus</i>
por: Maria Miklasińska-Majdanik
Publicado: (2021)

First Report of the Plasmid-mediated <i>fosB</i> Gene in <i>Enterococcus faecalis</i> from Pigs
por: Xiaoming Wang, et al.
Publicado: (2021)

Enhanced Resistance of <i>atbzip62</i> against <i>Pseudomonas syringae</i> pv. <i>tomato</i> Suggests Negative Regulation of Plant Basal Defense and Systemic Acquired Resistance by <i>AtbZIP62</i> Transcription Factor
por: Rizwana Begum Syed Nabi, et al.
Publicado: (2021)

Extraintestinal Pathogenic <i>Escherichia coli</i>: Virulence Factors and Antibiotic Resistance
por: Valerio M. Sora, et al.
Publicado: (2021)

Screening of <i>Amaranthus</i> sp. Varieties for Resistance to Bacterial Wilt Caused by <i>Ralstonia solanacearum</i>
por: Rachidatou Sikirou, et al.
Publicado: (2021)

Heteroresistance to Amikacin in Carbapenem-Resistant Klebsiella pneumoniae Strains
por: Feiyang Zhang, et al.
Publicado: (2021)

Presence of Tetracycline and Sulfonamide Resistance Genes in <i>Salmonella</i> spp.: Literature Review
por: Sabrina Lunara Santos Pavelquesi, et al.
Publicado: (2021)

Molecular genetic characteristics of the carbapenem resistant <i>Klebsiella pneumoniae KP254</i> strain as a representative of the highly virulent strain evolutionary branch
por: A. E. Alekseeva, et al.
Publicado: (2021)

Next-generation sequencing of drug resistant <i>Mycobacterium tuberculosis</i> clinical isolates in low-incidence countries
por: E. Sodja, et al.
Publicado: (2020)

Relationship between the Biofilm-Forming Capacity and Antimicrobial Resistance in Clinical <i>Acinetobacter baumannii</i> Isolates: Results from a Laboratory-Based In Vitro Study
por: Matthew Gavino Donadu, et al.
Publicado: (2021)

Effective Treatment against ESBL-Producing <i>Klebsiella pneumoniae</i> through Synergism of the Photodynamic Activity of Re (I) Compounds with Beta-Lactams
por: Iván A. González, et al.
Publicado: (2021)