Ultrasound-assisted multicomponent synthesis of heterocycles in water – A review

Ultrasound-assisted multicomponent reactions in water are great implements for the development of bioactive compounds. The methodologies for the synthesis of different heterocyclic molecules have acquired enormous attention. Many such techniques are energy-intensive and associated with hazardous che...

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Autores principales:	Ramakanth Pagadala, Venkatesan Kasi, Nhlanhla Gracious Shabalala, Sreekantha B. Jonnalagadda
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2022
Materias:	Water as a solvent Ultrasonic irradiation One-Pot Multicomponent reaction N-, O-, and S-Heterocycles Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/f2a9364c906c4d3db6c0edd126dfc7a3
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spelling	oai:doaj.org-article:f2a9364c906c4d3db6c0edd126dfc7a32021-11-20T04:58:15ZUltrasound-assisted multicomponent synthesis of heterocycles in water – A review1878-535210.1016/j.arabjc.2021.103544https://doaj.org/article/f2a9364c906c4d3db6c0edd126dfc7a32022-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1878535221005591https://doaj.org/toc/1878-5352Ultrasound-assisted multicomponent reactions in water are great implements for the development of bioactive compounds. The methodologies for the synthesis of different heterocyclic molecules have acquired enormous attention. Many such techniques are energy-intensive and associated with hazardous chemicals, solvents, expensive work-ups. Low yields and multi-step schemes generate huge organic waste. Hence, researchers thus focussed on benign and eco-friendly techniques to assemble heterocyclic analogs and drug molecules. The ultrasound-assisted synthesis of the target organic moieties frequently facilitates higher product yields than other methodologies. This review is focused on ultrasound-aided multicomponent reactions for synthesizing varied nitrogen-, oxygen-, and sulfur-containing heterocyclic compounds using water as the solvent. The advantages and limitations with respect to yields and reaction conditions are discussed. This evaluation covered the literature reports from 2014 to date.Ramakanth PagadalaVenkatesan KasiNhlanhla Gracious ShabalalaSreekantha B. JonnalagaddaElsevierarticleWater as a solventUltrasonic irradiationOne-PotMulticomponent reactionN-, O-, and S-HeterocyclesChemistryQD1-999ENArabian Journal of Chemistry, Vol 15, Iss 1, Pp 103544- (2022)
institution	DOAJ
collection	DOAJ
language	EN
topic	Water as a solvent Ultrasonic irradiation One-Pot Multicomponent reaction N-, O-, and S-Heterocycles Chemistry QD1-999
spellingShingle	Water as a solvent Ultrasonic irradiation One-Pot Multicomponent reaction N-, O-, and S-Heterocycles Chemistry QD1-999 Ramakanth Pagadala Venkatesan Kasi Nhlanhla Gracious Shabalala Sreekantha B. Jonnalagadda Ultrasound-assisted multicomponent synthesis of heterocycles in water – A review
description	Ultrasound-assisted multicomponent reactions in water are great implements for the development of bioactive compounds. The methodologies for the synthesis of different heterocyclic molecules have acquired enormous attention. Many such techniques are energy-intensive and associated with hazardous chemicals, solvents, expensive work-ups. Low yields and multi-step schemes generate huge organic waste. Hence, researchers thus focussed on benign and eco-friendly techniques to assemble heterocyclic analogs and drug molecules. The ultrasound-assisted synthesis of the target organic moieties frequently facilitates higher product yields than other methodologies. This review is focused on ultrasound-aided multicomponent reactions for synthesizing varied nitrogen-, oxygen-, and sulfur-containing heterocyclic compounds using water as the solvent. The advantages and limitations with respect to yields and reaction conditions are discussed. This evaluation covered the literature reports from 2014 to date.
format	article
author	Ramakanth Pagadala Venkatesan Kasi Nhlanhla Gracious Shabalala Sreekantha B. Jonnalagadda
author_facet	Ramakanth Pagadala Venkatesan Kasi Nhlanhla Gracious Shabalala Sreekantha B. Jonnalagadda
author_sort	Ramakanth Pagadala
title	Ultrasound-assisted multicomponent synthesis of heterocycles in water – A review
title_short	Ultrasound-assisted multicomponent synthesis of heterocycles in water – A review
title_full	Ultrasound-assisted multicomponent synthesis of heterocycles in water – A review
title_fullStr	Ultrasound-assisted multicomponent synthesis of heterocycles in water – A review
title_full_unstemmed	Ultrasound-assisted multicomponent synthesis of heterocycles in water – A review
title_sort	ultrasound-assisted multicomponent synthesis of heterocycles in water – a review
publisher	Elsevier
publishDate	2022
url	https://doaj.org/article/f2a9364c906c4d3db6c0edd126dfc7a3
work_keys_str_mv	AT ramakanthpagadala ultrasoundassistedmulticomponentsynthesisofheterocyclesinwaterareview AT venkatesankasi ultrasoundassistedmulticomponentsynthesisofheterocyclesinwaterareview AT nhlanhlagraciousshabalala ultrasoundassistedmulticomponentsynthesisofheterocyclesinwaterareview AT sreekanthabjonnalagadda ultrasoundassistedmulticomponentsynthesisofheterocyclesinwaterareview
_version_	1718419750543949824

Ultrasound-assisted multicomponent synthesis of heterocycles in water – A review

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