Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells
Higher-order chromatin organization regulates the expression of transcriptional programs that control cell function. Here, the authors show that chromatin interaction profiles and nuclear positions at developmental gene loci differ between human somatic and pluripotent stem cells.
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Nature Portfolio
2017
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oai:doaj.org-article:f2abb74fe82443a5a79daa922416e7d62021-12-02T14:42:43ZStructural and spatial chromatin features at developmental gene loci in human pluripotent stem cells10.1038/s41467-017-01679-x2041-1723https://doaj.org/article/f2abb74fe82443a5a79daa922416e7d62017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01679-xhttps://doaj.org/toc/2041-1723Higher-order chromatin organization regulates the expression of transcriptional programs that control cell function. Here, the authors show that chromatin interaction profiles and nuclear positions at developmental gene loci differ between human somatic and pluripotent stem cells.Hiroki IkedaMasamitsu SoneShinya YamanakaTakuya YamamotoNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017) |
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Science Q Hiroki Ikeda Masamitsu Sone Shinya Yamanaka Takuya Yamamoto Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells |
description |
Higher-order chromatin organization regulates the expression of transcriptional programs that control cell function. Here, the authors show that chromatin interaction profiles and nuclear positions at developmental gene loci differ between human somatic and pluripotent stem cells. |
format |
article |
author |
Hiroki Ikeda Masamitsu Sone Shinya Yamanaka Takuya Yamamoto |
author_facet |
Hiroki Ikeda Masamitsu Sone Shinya Yamanaka Takuya Yamamoto |
author_sort |
Hiroki Ikeda |
title |
Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells |
title_short |
Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells |
title_full |
Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells |
title_fullStr |
Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells |
title_full_unstemmed |
Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells |
title_sort |
structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/f2abb74fe82443a5a79daa922416e7d6 |
work_keys_str_mv |
AT hirokiikeda structuralandspatialchromatinfeaturesatdevelopmentalgenelociinhumanpluripotentstemcells AT masamitsusone structuralandspatialchromatinfeaturesatdevelopmentalgenelociinhumanpluripotentstemcells AT shinyayamanaka structuralandspatialchromatinfeaturesatdevelopmentalgenelociinhumanpluripotentstemcells AT takuyayamamoto structuralandspatialchromatinfeaturesatdevelopmentalgenelociinhumanpluripotentstemcells |
_version_ |
1718389606144016384 |