Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells

Higher-order chromatin organization regulates the expression of transcriptional programs that control cell function. Here, the authors show that chromatin interaction profiles and nuclear positions at developmental gene loci differ between human somatic and pluripotent stem cells.

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Autores principales: Hiroki Ikeda, Masamitsu Sone, Shinya Yamanaka, Takuya Yamamoto
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/f2abb74fe82443a5a79daa922416e7d6
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spelling oai:doaj.org-article:f2abb74fe82443a5a79daa922416e7d62021-12-02T14:42:43ZStructural and spatial chromatin features at developmental gene loci in human pluripotent stem cells10.1038/s41467-017-01679-x2041-1723https://doaj.org/article/f2abb74fe82443a5a79daa922416e7d62017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01679-xhttps://doaj.org/toc/2041-1723Higher-order chromatin organization regulates the expression of transcriptional programs that control cell function. Here, the authors show that chromatin interaction profiles and nuclear positions at developmental gene loci differ between human somatic and pluripotent stem cells.Hiroki IkedaMasamitsu SoneShinya YamanakaTakuya YamamotoNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Hiroki Ikeda
Masamitsu Sone
Shinya Yamanaka
Takuya Yamamoto
Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells
description Higher-order chromatin organization regulates the expression of transcriptional programs that control cell function. Here, the authors show that chromatin interaction profiles and nuclear positions at developmental gene loci differ between human somatic and pluripotent stem cells.
format article
author Hiroki Ikeda
Masamitsu Sone
Shinya Yamanaka
Takuya Yamamoto
author_facet Hiroki Ikeda
Masamitsu Sone
Shinya Yamanaka
Takuya Yamamoto
author_sort Hiroki Ikeda
title Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells
title_short Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells
title_full Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells
title_fullStr Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells
title_full_unstemmed Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells
title_sort structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/f2abb74fe82443a5a79daa922416e7d6
work_keys_str_mv AT hirokiikeda structuralandspatialchromatinfeaturesatdevelopmentalgenelociinhumanpluripotentstemcells
AT masamitsusone structuralandspatialchromatinfeaturesatdevelopmentalgenelociinhumanpluripotentstemcells
AT shinyayamanaka structuralandspatialchromatinfeaturesatdevelopmentalgenelociinhumanpluripotentstemcells
AT takuyayamamoto structuralandspatialchromatinfeaturesatdevelopmentalgenelociinhumanpluripotentstemcells
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