Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells
Higher-order chromatin organization regulates the expression of transcriptional programs that control cell function. Here, the authors show that chromatin interaction profiles and nuclear positions at developmental gene loci differ between human somatic and pluripotent stem cells.
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Main Authors: | Hiroki Ikeda, Masamitsu Sone, Shinya Yamanaka, Takuya Yamamoto |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
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Subjects: | |
Online Access: | https://doaj.org/article/f2abb74fe82443a5a79daa922416e7d6 |
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