G Protein–Coupled Estrogen Receptor 30 Reduces Transverse Aortic Constriction–Induced Myocardial Fibrosis in Aged Female Mice by Inhibiting the ERK1/2 -MMP-9 Signaling Pathway

The incidence of cardiovascular diseases was significantly increased in postmenopausal women. The protection of estrogen in the cardiovascular system has been further reported for decades. Although menopausal hormone therapy has been used in many clinical trials, the debatable results indicate that...

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Autores principales:	Xiaowu Wang, Jipeng Ma, Shuaishuai Zhang, Zilin Li, Ziwei Hong, Liqing Jiang, Weixun Duan, Jincheng Liu
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	G protein–coupled estrogen receptor 30 (GPR30) transverse aortic constriction MMP-9 aged female cardiac fibrosis Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/f2b43bf790a04a4db24683e3e1dc2ca7
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G Protein–Coupled Estrogen Receptor 30 Reduces Transverse Aortic Constriction–Induced Myocardial Fibrosis in Aged Female Mice by Inhibiting the ERK1/2 -MMP-9 Signaling Pathway

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