Cost-effectiveness of procedure-less intragastric balloon therapy as substitute or complement to bariatric surgery.

<h4>Background</h4>Procedure-less intragastric balloon (PIGB) eliminates costs and risks of endoscopic placement/removal and involves lower risk of serious complications compared with bariatric surgery, albeit with lower weight loss. Given the vast unmet need for obesity treatment, an im...

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Autores principales:	Shweta Mital, Hai V Nguyen
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/f2bf43f089d040419852e5024757d99c
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spelling	oai:doaj.org-article:f2bf43f089d040419852e5024757d99c2021-12-02T20:04:49ZCost-effectiveness of procedure-less intragastric balloon therapy as substitute or complement to bariatric surgery.1932-620310.1371/journal.pone.0254063https://doaj.org/article/f2bf43f089d040419852e5024757d99c2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0254063https://doaj.org/toc/1932-6203<h4>Background</h4>Procedure-less intragastric balloon (PIGB) eliminates costs and risks of endoscopic placement/removal and involves lower risk of serious complications compared with bariatric surgery, albeit with lower weight loss. Given the vast unmet need for obesity treatment, an important question is whether PIGB treatment is cost-effective-either stand-alone or as a bridge to bariatric surgery.<h4>Methods</h4>We developed a microsimulation model to compare the costs and effectiveness of six treatment strategies: PIGB, gastric bypass or sleeve gastrectomy as stand-alone treatments, PIGB as a bridge to gastric bypass or sleeve gastrectomy, and no treatment.<h4>Results</h4>PIGB as a bridge to bariatric surgery is less costly and more effective than bariatric surgery alone as it helps to achieve a lower post-operative BMI. Of the six strategies, PIGB as a bridge to sleeve gastrectomy is the most cost-effective with an ICER of $3,781 per QALY gained. While PIGB alone is not cost-effective compared with bariatric surgery, it is cost-effective compared with no treatment with an ICER of $21,711 per QALY.<h4>Conclusions</h4>PIGB can yield cost savings and improve health outcomes if used as a bridge to bariatric surgery and is cost-effective as a stand-alone treatment for patients lacking access or unwilling to undergo surgery.Shweta MitalHai V NguyenPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 7, p e0254063 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Shweta Mital Hai V Nguyen Cost-effectiveness of procedure-less intragastric balloon therapy as substitute or complement to bariatric surgery.
description	<h4>Background</h4>Procedure-less intragastric balloon (PIGB) eliminates costs and risks of endoscopic placement/removal and involves lower risk of serious complications compared with bariatric surgery, albeit with lower weight loss. Given the vast unmet need for obesity treatment, an important question is whether PIGB treatment is cost-effective-either stand-alone or as a bridge to bariatric surgery.<h4>Methods</h4>We developed a microsimulation model to compare the costs and effectiveness of six treatment strategies: PIGB, gastric bypass or sleeve gastrectomy as stand-alone treatments, PIGB as a bridge to gastric bypass or sleeve gastrectomy, and no treatment.<h4>Results</h4>PIGB as a bridge to bariatric surgery is less costly and more effective than bariatric surgery alone as it helps to achieve a lower post-operative BMI. Of the six strategies, PIGB as a bridge to sleeve gastrectomy is the most cost-effective with an ICER of $3,781 per QALY gained. While PIGB alone is not cost-effective compared with bariatric surgery, it is cost-effective compared with no treatment with an ICER of $21,711 per QALY.<h4>Conclusions</h4>PIGB can yield cost savings and improve health outcomes if used as a bridge to bariatric surgery and is cost-effective as a stand-alone treatment for patients lacking access or unwilling to undergo surgery.
format	article
author	Shweta Mital Hai V Nguyen
author_facet	Shweta Mital Hai V Nguyen
author_sort	Shweta Mital
title	Cost-effectiveness of procedure-less intragastric balloon therapy as substitute or complement to bariatric surgery.
title_short	Cost-effectiveness of procedure-less intragastric balloon therapy as substitute or complement to bariatric surgery.
title_full	Cost-effectiveness of procedure-less intragastric balloon therapy as substitute or complement to bariatric surgery.
title_fullStr	Cost-effectiveness of procedure-less intragastric balloon therapy as substitute or complement to bariatric surgery.
title_full_unstemmed	Cost-effectiveness of procedure-less intragastric balloon therapy as substitute or complement to bariatric surgery.
title_sort	cost-effectiveness of procedure-less intragastric balloon therapy as substitute or complement to bariatric surgery.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/f2bf43f089d040419852e5024757d99c
work_keys_str_mv	AT shwetamital costeffectivenessofprocedurelessintragastricballoontherapyassubstituteorcomplementtobariatricsurgery AT haivnguyen costeffectivenessofprocedurelessintragastricballoontherapyassubstituteorcomplementtobariatricsurgery
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Cost-effectiveness of procedure-less intragastric balloon therapy as substitute or complement to bariatric surgery.

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