Determinants of SARS-CoV-2 infection in Italian healthcare workers: a multicenter study

Abstract Healthcare workers (HCWs) are at increased risk of being infected with SARS-CoV-2, yet limited information is available on risk factors of infection. We pooled data on occupational surveillance of 10,654 HCW who were tested for SARS-CoV-2 infection in six Italian centers. Information was av...

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Autores principales:	Paolo Boffetta, Francesco Violante, Paolo Durando, Giuseppe De Palma, Enrico Pira, Luigi Vimercati, Alfonso Cristaudo, Giancarlo Icardi, Emma Sala, Maurizio Coggiola, Silvio Tafuri, Vittorio Gattini, Pietro Apostoli, Giovanna Spatari, Working Group on SARS-CoV-2 Infection in Italian Healthcare Workers
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/f2d0797690e04466aef721cbeded55c3
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spelling	oai:doaj.org-article:f2d0797690e04466aef721cbeded55c32021-12-02T11:37:22ZDeterminants of SARS-CoV-2 infection in Italian healthcare workers: a multicenter study10.1038/s41598-021-85215-42045-2322https://doaj.org/article/f2d0797690e04466aef721cbeded55c32021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-85215-4https://doaj.org/toc/2045-2322Abstract Healthcare workers (HCWs) are at increased risk of being infected with SARS-CoV-2, yet limited information is available on risk factors of infection. We pooled data on occupational surveillance of 10,654 HCW who were tested for SARS-CoV-2 infection in six Italian centers. Information was available on demographics, job title, department of employment, source of exposure, use of personal protective equipment (PPEs), and COVID-19-related symptoms. We fitted multivariable logistic regression models to calculate odds ratios and 95% confidence intervals of infection. The prevalence of infection ranged from 3.0 to 22.0%, and was correlated with that of the respective areas. Women were at lower risk of infection compared to men. Fever, cough, dyspnea and malaise were the symptoms most strongly associated with infection, together with anosmia and ageusia. No differences in the risk of infection were detected according to job title, or working in a COVID-19 designated department. Reported contact with a patient inside or outside the workplace was a risk factor. Use of a mask was strongly protective against risk of infection as was use of gloves. The use of a mask by the source of exposure (patient or colleague) had an independent effect in reducing infection risk.Paolo BoffettaFrancesco ViolantePaolo DurandoGiuseppe De PalmaEnrico PiraLuigi VimercatiAlfonso CristaudoGiancarlo IcardiEmma SalaMaurizio CoggiolaSilvio TafuriVittorio GattiniPietro ApostoliGiovanna SpatariWorking Group on SARS-CoV-2 Infection in Italian Healthcare WorkersNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Paolo Boffetta Francesco Violante Paolo Durando Giuseppe De Palma Enrico Pira Luigi Vimercati Alfonso Cristaudo Giancarlo Icardi Emma Sala Maurizio Coggiola Silvio Tafuri Vittorio Gattini Pietro Apostoli Giovanna Spatari Working Group on SARS-CoV-2 Infection in Italian Healthcare Workers Determinants of SARS-CoV-2 infection in Italian healthcare workers: a multicenter study
description	Abstract Healthcare workers (HCWs) are at increased risk of being infected with SARS-CoV-2, yet limited information is available on risk factors of infection. We pooled data on occupational surveillance of 10,654 HCW who were tested for SARS-CoV-2 infection in six Italian centers. Information was available on demographics, job title, department of employment, source of exposure, use of personal protective equipment (PPEs), and COVID-19-related symptoms. We fitted multivariable logistic regression models to calculate odds ratios and 95% confidence intervals of infection. The prevalence of infection ranged from 3.0 to 22.0%, and was correlated with that of the respective areas. Women were at lower risk of infection compared to men. Fever, cough, dyspnea and malaise were the symptoms most strongly associated with infection, together with anosmia and ageusia. No differences in the risk of infection were detected according to job title, or working in a COVID-19 designated department. Reported contact with a patient inside or outside the workplace was a risk factor. Use of a mask was strongly protective against risk of infection as was use of gloves. The use of a mask by the source of exposure (patient or colleague) had an independent effect in reducing infection risk.
format	article
author	Paolo Boffetta Francesco Violante Paolo Durando Giuseppe De Palma Enrico Pira Luigi Vimercati Alfonso Cristaudo Giancarlo Icardi Emma Sala Maurizio Coggiola Silvio Tafuri Vittorio Gattini Pietro Apostoli Giovanna Spatari Working Group on SARS-CoV-2 Infection in Italian Healthcare Workers
author_facet	Paolo Boffetta Francesco Violante Paolo Durando Giuseppe De Palma Enrico Pira Luigi Vimercati Alfonso Cristaudo Giancarlo Icardi Emma Sala Maurizio Coggiola Silvio Tafuri Vittorio Gattini Pietro Apostoli Giovanna Spatari Working Group on SARS-CoV-2 Infection in Italian Healthcare Workers
author_sort	Paolo Boffetta
title	Determinants of SARS-CoV-2 infection in Italian healthcare workers: a multicenter study
title_short	Determinants of SARS-CoV-2 infection in Italian healthcare workers: a multicenter study
title_full	Determinants of SARS-CoV-2 infection in Italian healthcare workers: a multicenter study
title_fullStr	Determinants of SARS-CoV-2 infection in Italian healthcare workers: a multicenter study
title_full_unstemmed	Determinants of SARS-CoV-2 infection in Italian healthcare workers: a multicenter study
title_sort	determinants of sars-cov-2 infection in italian healthcare workers: a multicenter study
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/f2d0797690e04466aef721cbeded55c3
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Determinants of SARS-CoV-2 infection in Italian healthcare workers: a multicenter study

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