A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models

Astrocytes can have protective or detrimental effects on neurons during injury, but the molecular mechanisms that determine these different states are unresolved. Here the authors identify a pathway via neuronal EphB1 that induces neuroprotective signalling in astrocytes through ephrin-B1 mediated S...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Giulia E. Tyzack, Claire E. Hall, Christopher R. Sibley, Tomasz Cymes, Serhiy Forostyak, Giulia Carlino, Ione F. Meyer, Giampietro Schiavo, Su-Chun Zhang, George M. Gibbons, Jia Newcombe, Rickie Patani, András Lakatos
Format: article
Langue:EN
Publié: Nature Portfolio 2017
Sujets:
Q
Accès en ligne:https://doaj.org/article/f2e3526b9f5c450291eab266e252c78a
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!