Impact of Multidisciplinary Team Escalating Approach on Antibiotic Stewardship in the United Arab Emirates

Antimicrobial stewardship programs (ASP) are an essential strategy to combat antimicrobial resistance. This study aimed to measure the impact of an ASP multidisciplinary team (MDT) escalating intervention on improvement of clinical, microbiological, and other measured outcomes in hospitalised adult...

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Autores principales:	Ahmed A. Sadeq, Jinan M. Shamseddine, Zahir Osman Eltahir Babiker, Emmanuel Fru Nsutebu, Marleine B. Moukarzel, Barbara R. Conway, Syed Shahzad Hasan, Geraldine M. Conlon-Bingham, Mamoon A. Aldeyab
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	antimicrobial stewardship program multidisciplinary team days of therapy length of stay daily defined doses readmission Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/f2e66cf18ed14aba887234cada326387
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spelling	oai:doaj.org-article:f2e66cf18ed14aba887234cada3263872021-11-25T16:22:01ZImpact of Multidisciplinary Team Escalating Approach on Antibiotic Stewardship in the United Arab Emirates10.3390/antibiotics101112892079-6382https://doaj.org/article/f2e66cf18ed14aba887234cada3263872021-10-01T00:00:00Zhttps://www.mdpi.com/2079-6382/10/11/1289https://doaj.org/toc/2079-6382Antimicrobial stewardship programs (ASP) are an essential strategy to combat antimicrobial resistance. This study aimed to measure the impact of an ASP multidisciplinary team (MDT) escalating intervention on improvement of clinical, microbiological, and other measured outcomes in hospitalised adult patients from medical, intensive care, and burns units. The escalating intervention reviewed the patients’ cases in the intervention group through the clinical pharmacists in the wards and escalated complex cases to ID clinical pharmacist and ID physicians when needed, while only special cases required direct infectious disease (ID) physicians review. Both non-intervention and intervention groups were each followed up for six months. The study involved a total of 3000 patients, with 1340 (45%) representing the intervention group who received a total of 5669 interventions. In the intervention group, a significant reduction in length of hospital stay (<i>p</i> < 0.01), readmission (<i>p</i> < 0.01), and mortality rates (<i>p</i> < 0.01) was observed. Antibiotic use of the WHO AWaRe Reserve group decreased in the intervention group (relative rate change = 0.88). Intravenous to oral antibiotic ratio in the medical ward decreased from 4.8 to 4.1. The presented ASP MDT intervention, utilizing an escalating approach, successfully improved several clinical and other measured outcomes, demonstrating the significant contribution of clinical pharmacists atimproving antibiotic use and informing antimicrobial stewardship.Ahmed A. SadeqJinan M. ShamseddineZahir Osman Eltahir BabikerEmmanuel Fru NsutebuMarleine B. MoukarzelBarbara R. ConwaySyed Shahzad HasanGeraldine M. Conlon-BinghamMamoon A. AldeyabMDPI AGarticleantimicrobial stewardship programmultidisciplinary teamdays of therapylength of staydaily defined dosesreadmissionTherapeutics. PharmacologyRM1-950ENAntibiotics, Vol 10, Iss 1289, p 1289 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	antimicrobial stewardship program multidisciplinary team days of therapy length of stay daily defined doses readmission Therapeutics. Pharmacology RM1-950
spellingShingle	antimicrobial stewardship program multidisciplinary team days of therapy length of stay daily defined doses readmission Therapeutics. Pharmacology RM1-950 Ahmed A. Sadeq Jinan M. Shamseddine Zahir Osman Eltahir Babiker Emmanuel Fru Nsutebu Marleine B. Moukarzel Barbara R. Conway Syed Shahzad Hasan Geraldine M. Conlon-Bingham Mamoon A. Aldeyab Impact of Multidisciplinary Team Escalating Approach on Antibiotic Stewardship in the United Arab Emirates
description	Antimicrobial stewardship programs (ASP) are an essential strategy to combat antimicrobial resistance. This study aimed to measure the impact of an ASP multidisciplinary team (MDT) escalating intervention on improvement of clinical, microbiological, and other measured outcomes in hospitalised adult patients from medical, intensive care, and burns units. The escalating intervention reviewed the patients’ cases in the intervention group through the clinical pharmacists in the wards and escalated complex cases to ID clinical pharmacist and ID physicians when needed, while only special cases required direct infectious disease (ID) physicians review. Both non-intervention and intervention groups were each followed up for six months. The study involved a total of 3000 patients, with 1340 (45%) representing the intervention group who received a total of 5669 interventions. In the intervention group, a significant reduction in length of hospital stay (<i>p</i> < 0.01), readmission (<i>p</i> < 0.01), and mortality rates (<i>p</i> < 0.01) was observed. Antibiotic use of the WHO AWaRe Reserve group decreased in the intervention group (relative rate change = 0.88). Intravenous to oral antibiotic ratio in the medical ward decreased from 4.8 to 4.1. The presented ASP MDT intervention, utilizing an escalating approach, successfully improved several clinical and other measured outcomes, demonstrating the significant contribution of clinical pharmacists atimproving antibiotic use and informing antimicrobial stewardship.
format	article
author	Ahmed A. Sadeq Jinan M. Shamseddine Zahir Osman Eltahir Babiker Emmanuel Fru Nsutebu Marleine B. Moukarzel Barbara R. Conway Syed Shahzad Hasan Geraldine M. Conlon-Bingham Mamoon A. Aldeyab
author_facet	Ahmed A. Sadeq Jinan M. Shamseddine Zahir Osman Eltahir Babiker Emmanuel Fru Nsutebu Marleine B. Moukarzel Barbara R. Conway Syed Shahzad Hasan Geraldine M. Conlon-Bingham Mamoon A. Aldeyab
author_sort	Ahmed A. Sadeq
title	Impact of Multidisciplinary Team Escalating Approach on Antibiotic Stewardship in the United Arab Emirates
title_short	Impact of Multidisciplinary Team Escalating Approach on Antibiotic Stewardship in the United Arab Emirates
title_full	Impact of Multidisciplinary Team Escalating Approach on Antibiotic Stewardship in the United Arab Emirates
title_fullStr	Impact of Multidisciplinary Team Escalating Approach on Antibiotic Stewardship in the United Arab Emirates
title_full_unstemmed	Impact of Multidisciplinary Team Escalating Approach on Antibiotic Stewardship in the United Arab Emirates
title_sort	impact of multidisciplinary team escalating approach on antibiotic stewardship in the united arab emirates
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/f2e66cf18ed14aba887234cada326387
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Impact of Multidisciplinary Team Escalating Approach on Antibiotic Stewardship in the United Arab Emirates

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