COVID-19 and kidneys
COVID-19 poses a real threat to patients with comorbid conditions such as diabetes mellitus (DM), hypertension, cardiovascular, renal or hepatic disorders. Kidney damage is very likely in people with diabetes who have undergone a new infection, and the risk of developing acute renal injury is associ...
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Endocrinology Research Centre
2020
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oai:doaj.org-article:f2f4255662db4d33a6e25190c1210a3e2021-11-14T09:00:23ZCOVID-19 and kidneys2072-03512072-037810.14341/DM12506https://doaj.org/article/f2f4255662db4d33a6e25190c1210a3e2020-08-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/12506https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378COVID-19 poses a real threat to patients with comorbid conditions such as diabetes mellitus (DM), hypertension, cardiovascular, renal or hepatic disorders. Kidney damage is very likely in people with diabetes who have undergone a new infection, and the risk of developing acute renal injury is associated with mortality. Potential mechanisms of kidney involvement in the clinical picture of the disease may include cytokine damage, cross-organ damage, and systemic effects that determine the treatment strategy. These mechanisms are closely interrelated and are important for individuals on extracorporeal therapy and kidney transplants. Autopsy data provide evidence of SARS-CoV-2 virus invasion into kidney tissue with damage to tubular epithelium cells and podocytes, and red blood cell aggregation in severely COVID-19 patients. By including individuals with chronic kidney disease in planned COVID-19 research protocols, an evidence base for effective and safe treatments can be generated.M. S. ShamkhalovaN. G. MokryshevaM. V. ShestakovaEndocrinology Research Centrearticlecovid-19diabetes mellitusacute kidney injurydialysiskidney transplantNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 23, Iss 3, Pp 235-241 (2020) |
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DOAJ |
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DOAJ |
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EN RU |
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covid-19 diabetes mellitus acute kidney injury dialysis kidney transplant Nutritional diseases. Deficiency diseases RC620-627 |
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covid-19 diabetes mellitus acute kidney injury dialysis kidney transplant Nutritional diseases. Deficiency diseases RC620-627 M. S. Shamkhalova N. G. Mokrysheva M. V. Shestakova COVID-19 and kidneys |
| description |
COVID-19 poses a real threat to patients with comorbid conditions such as diabetes mellitus (DM), hypertension, cardiovascular, renal or hepatic disorders. Kidney damage is very likely in people with diabetes who have undergone a new infection, and the risk of developing acute renal injury is associated with mortality. Potential mechanisms of kidney involvement in the clinical picture of the disease may include cytokine damage, cross-organ damage, and systemic effects that determine the treatment strategy. These mechanisms are closely interrelated and are important for individuals on extracorporeal therapy and kidney transplants. Autopsy data provide evidence of SARS-CoV-2 virus invasion into kidney tissue with damage to tubular epithelium cells and podocytes, and red blood cell aggregation in severely COVID-19 patients. By including individuals with chronic kidney disease in planned COVID-19 research protocols, an evidence base for effective and safe treatments can be generated. |
| format |
article |
| author |
M. S. Shamkhalova N. G. Mokrysheva M. V. Shestakova |
| author_facet |
M. S. Shamkhalova N. G. Mokrysheva M. V. Shestakova |
| author_sort |
M. S. Shamkhalova |
| title |
COVID-19 and kidneys |
| title_short |
COVID-19 and kidneys |
| title_full |
COVID-19 and kidneys |
| title_fullStr |
COVID-19 and kidneys |
| title_full_unstemmed |
COVID-19 and kidneys |
| title_sort |
covid-19 and kidneys |
| publisher |
Endocrinology Research Centre |
| publishDate |
2020 |
| url |
https://doaj.org/article/f2f4255662db4d33a6e25190c1210a3e |
| work_keys_str_mv |
AT msshamkhalova covid19andkidneys AT ngmokrysheva covid19andkidneys AT mvshestakova covid19andkidneys |
| _version_ |
1718429501297262592 |