Comprehensive family therapy: an effective approach for cognitive rehabilitation in schizophrenia

Jun Cai,1 Yi Zhu,1 Weibo Zhang,1 Yanfeng Wang,1 Chen Zhang2 1Center for Disease Control and Prevention, Shanghai Mental Health Center, 2Schizophrenia Program, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China Background:...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Cai J, Zhu Y, Zhang W, Wang Y, Zhang C
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/f2f8000a19a24dbfaadcf00433f552b6
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f2f8000a19a24dbfaadcf00433f552b6
record_format	dspace
spelling	oai:doaj.org-article:f2f8000a19a24dbfaadcf00433f552b62021-12-02T11:34:14ZComprehensive family therapy: an effective approach for cognitive rehabilitation in schizophrenia1178-2021https://doaj.org/article/f2f8000a19a24dbfaadcf00433f552b62015-05-01T00:00:00Zhttp://www.dovepress.com/comprehensive-family-therapy-an-effective-approach-for-cognitive-rehab-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Jun Cai,1 Yi Zhu,1 Weibo Zhang,1 Yanfeng Wang,1 Chen Zhang2 1Center for Disease Control and Prevention, Shanghai Mental Health Center, 2Schizophrenia Program, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China Background: Antipsychotic medication has limited abilities to improve the cognitive impairments that accompany schizophrenia. Adding psychosocial treatment may result in marked improvements in cognitive function, as compared to antipsychotic treatment alone. We hypothesized that a combination of individual and family interventions may be a useful cognitive rehabilitation paradigm for schizophrenia.  Materials and methods: An 18-month follow-up clinical trial of 256 stabilized patients with schizophrenia at six communities in Shanghai, People’s Republic of China were randomly assigned to into either a comprehensive family therapy (CFT) group or a usual daily care (UDC) group. The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) and the Positive and Negative Syndrome Scale (PANSS) were the primary outcome instruments for this study.  Results: There was no significant difference between the CFT and UDC for all demographic characteristics at the baseline assessment. During the 18-month follow-up observation, changes in RBANS total score indicated that patients undergoing CFT showed greater improvement from baseline to the follow-up assessments in cognitive function than those in the UDC group (F=9.77, P=0.002). Post hoc analysis showed that the CFT group presented with significant differences in the RBANS total score, immediate memory, visuospatial skill, language, attention, and delayed memory sections compared with the UDC after 18 months of follow-up (all P<0.01).Conclusion: Our findings suggest that CFT can be easily adapted and may prove to be an effective approach for improving cognitive function in patients with schizophrenia. Our program provides a potential paradigm for cognitive rehabilitation for schizophrenia patients in the community. Keywords: cognitive function, comprehensive family therapy, schizophreniaCai JZhu YZhang WWang YZhang CDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2015, Iss default, Pp 1247-1253 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Cai J Zhu Y Zhang W Wang Y Zhang C Comprehensive family therapy: an effective approach for cognitive rehabilitation in schizophrenia
description	Jun Cai,1 Yi Zhu,1 Weibo Zhang,1 Yanfeng Wang,1 Chen Zhang2 1Center for Disease Control and Prevention, Shanghai Mental Health Center, 2Schizophrenia Program, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China Background: Antipsychotic medication has limited abilities to improve the cognitive impairments that accompany schizophrenia. Adding psychosocial treatment may result in marked improvements in cognitive function, as compared to antipsychotic treatment alone. We hypothesized that a combination of individual and family interventions may be a useful cognitive rehabilitation paradigm for schizophrenia.  Materials and methods: An 18-month follow-up clinical trial of 256 stabilized patients with schizophrenia at six communities in Shanghai, People’s Republic of China were randomly assigned to into either a comprehensive family therapy (CFT) group or a usual daily care (UDC) group. The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) and the Positive and Negative Syndrome Scale (PANSS) were the primary outcome instruments for this study.  Results: There was no significant difference between the CFT and UDC for all demographic characteristics at the baseline assessment. During the 18-month follow-up observation, changes in RBANS total score indicated that patients undergoing CFT showed greater improvement from baseline to the follow-up assessments in cognitive function than those in the UDC group (F=9.77, P=0.002). Post hoc analysis showed that the CFT group presented with significant differences in the RBANS total score, immediate memory, visuospatial skill, language, attention, and delayed memory sections compared with the UDC after 18 months of follow-up (all P<0.01).Conclusion: Our findings suggest that CFT can be easily adapted and may prove to be an effective approach for improving cognitive function in patients with schizophrenia. Our program provides a potential paradigm for cognitive rehabilitation for schizophrenia patients in the community. Keywords: cognitive function, comprehensive family therapy, schizophrenia
format	article
author	Cai J Zhu Y Zhang W Wang Y Zhang C
author_facet	Cai J Zhu Y Zhang W Wang Y Zhang C
author_sort	Cai J
title	Comprehensive family therapy: an effective approach for cognitive rehabilitation in schizophrenia
title_short	Comprehensive family therapy: an effective approach for cognitive rehabilitation in schizophrenia
title_full	Comprehensive family therapy: an effective approach for cognitive rehabilitation in schizophrenia
title_fullStr	Comprehensive family therapy: an effective approach for cognitive rehabilitation in schizophrenia
title_full_unstemmed	Comprehensive family therapy: an effective approach for cognitive rehabilitation in schizophrenia
title_sort	comprehensive family therapy: an effective approach for cognitive rehabilitation in schizophrenia
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/f2f8000a19a24dbfaadcf00433f552b6
work_keys_str_mv	AT caij comprehensivefamilytherapyaneffectiveapproachforcognitiverehabilitationinschizophrenia AT zhuy comprehensivefamilytherapyaneffectiveapproachforcognitiverehabilitationinschizophrenia AT zhangw comprehensivefamilytherapyaneffectiveapproachforcognitiverehabilitationinschizophrenia AT wangy comprehensivefamilytherapyaneffectiveapproachforcognitiverehabilitationinschizophrenia AT zhangc comprehensivefamilytherapyaneffectiveapproachforcognitiverehabilitationinschizophrenia
_version_	1718395856257810432

Comprehensive family therapy: an effective approach for cognitive rehabilitation in schizophrenia

Ejemplares similares