Wet-dry cycles enable the parallel origin of canonical and non-canonical nucleosides by continuous synthesis

How RNA building blocks have formed on an early Earth by a continuous process is still a mystery awaiting its solution. Here, the authors report that fluctuations of physical parameters like temperature and pH could have been enough to facilitate nucleoside formation from simple starting materials.

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Bibliographic Details
Main Authors: Sidney Becker, Christina Schneider, Hidenori Okamura, Antony Crisp, Tynchtyk Amatov, Milan Dejmek, Thomas Carell
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/f30b47cab3884e568cef79fb2ecc6324
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Summary:How RNA building blocks have formed on an early Earth by a continuous process is still a mystery awaiting its solution. Here, the authors report that fluctuations of physical parameters like temperature and pH could have been enough to facilitate nucleoside formation from simple starting materials.