Wet-dry cycles enable the parallel origin of canonical and non-canonical nucleosides by continuous synthesis

How RNA building blocks have formed on an early Earth by a continuous process is still a mystery awaiting its solution. Here, the authors report that fluctuations of physical parameters like temperature and pH could have been enough to facilitate nucleoside formation from simple starting materials.

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Autores principales: Sidney Becker, Christina Schneider, Hidenori Okamura, Antony Crisp, Tynchtyk Amatov, Milan Dejmek, Thomas Carell
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/f30b47cab3884e568cef79fb2ecc6324
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spelling oai:doaj.org-article:f30b47cab3884e568cef79fb2ecc63242021-12-02T14:39:46ZWet-dry cycles enable the parallel origin of canonical and non-canonical nucleosides by continuous synthesis10.1038/s41467-017-02639-12041-1723https://doaj.org/article/f30b47cab3884e568cef79fb2ecc63242018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02639-1https://doaj.org/toc/2041-1723How RNA building blocks have formed on an early Earth by a continuous process is still a mystery awaiting its solution. Here, the authors report that fluctuations of physical parameters like temperature and pH could have been enough to facilitate nucleoside formation from simple starting materials.Sidney BeckerChristina SchneiderHidenori OkamuraAntony CrispTynchtyk AmatovMilan DejmekThomas CarellNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sidney Becker
Christina Schneider
Hidenori Okamura
Antony Crisp
Tynchtyk Amatov
Milan Dejmek
Thomas Carell
Wet-dry cycles enable the parallel origin of canonical and non-canonical nucleosides by continuous synthesis
description How RNA building blocks have formed on an early Earth by a continuous process is still a mystery awaiting its solution. Here, the authors report that fluctuations of physical parameters like temperature and pH could have been enough to facilitate nucleoside formation from simple starting materials.
format article
author Sidney Becker
Christina Schneider
Hidenori Okamura
Antony Crisp
Tynchtyk Amatov
Milan Dejmek
Thomas Carell
author_facet Sidney Becker
Christina Schneider
Hidenori Okamura
Antony Crisp
Tynchtyk Amatov
Milan Dejmek
Thomas Carell
author_sort Sidney Becker
title Wet-dry cycles enable the parallel origin of canonical and non-canonical nucleosides by continuous synthesis
title_short Wet-dry cycles enable the parallel origin of canonical and non-canonical nucleosides by continuous synthesis
title_full Wet-dry cycles enable the parallel origin of canonical and non-canonical nucleosides by continuous synthesis
title_fullStr Wet-dry cycles enable the parallel origin of canonical and non-canonical nucleosides by continuous synthesis
title_full_unstemmed Wet-dry cycles enable the parallel origin of canonical and non-canonical nucleosides by continuous synthesis
title_sort wet-dry cycles enable the parallel origin of canonical and non-canonical nucleosides by continuous synthesis
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/f30b47cab3884e568cef79fb2ecc6324
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AT christinaschneider wetdrycyclesenabletheparalleloriginofcanonicalandnoncanonicalnucleosidesbycontinuoussynthesis
AT hidenoriokamura wetdrycyclesenabletheparalleloriginofcanonicalandnoncanonicalnucleosidesbycontinuoussynthesis
AT antonycrisp wetdrycyclesenabletheparalleloriginofcanonicalandnoncanonicalnucleosidesbycontinuoussynthesis
AT tynchtykamatov wetdrycyclesenabletheparalleloriginofcanonicalandnoncanonicalnucleosidesbycontinuoussynthesis
AT milandejmek wetdrycyclesenabletheparalleloriginofcanonicalandnoncanonicalnucleosidesbycontinuoussynthesis
AT thomascarell wetdrycyclesenabletheparalleloriginofcanonicalandnoncanonicalnucleosidesbycontinuoussynthesis
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