Wet-dry cycles enable the parallel origin of canonical and non-canonical nucleosides by continuous synthesis
How RNA building blocks have formed on an early Earth by a continuous process is still a mystery awaiting its solution. Here, the authors report that fluctuations of physical parameters like temperature and pH could have been enough to facilitate nucleoside formation from simple starting materials.
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Nature Portfolio
2018
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oai:doaj.org-article:f30b47cab3884e568cef79fb2ecc63242021-12-02T14:39:46ZWet-dry cycles enable the parallel origin of canonical and non-canonical nucleosides by continuous synthesis10.1038/s41467-017-02639-12041-1723https://doaj.org/article/f30b47cab3884e568cef79fb2ecc63242018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02639-1https://doaj.org/toc/2041-1723How RNA building blocks have formed on an early Earth by a continuous process is still a mystery awaiting its solution. Here, the authors report that fluctuations of physical parameters like temperature and pH could have been enough to facilitate nucleoside formation from simple starting materials.Sidney BeckerChristina SchneiderHidenori OkamuraAntony CrispTynchtyk AmatovMilan DejmekThomas CarellNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018) |
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Science Q Sidney Becker Christina Schneider Hidenori Okamura Antony Crisp Tynchtyk Amatov Milan Dejmek Thomas Carell Wet-dry cycles enable the parallel origin of canonical and non-canonical nucleosides by continuous synthesis |
description |
How RNA building blocks have formed on an early Earth by a continuous process is still a mystery awaiting its solution. Here, the authors report that fluctuations of physical parameters like temperature and pH could have been enough to facilitate nucleoside formation from simple starting materials. |
format |
article |
author |
Sidney Becker Christina Schneider Hidenori Okamura Antony Crisp Tynchtyk Amatov Milan Dejmek Thomas Carell |
author_facet |
Sidney Becker Christina Schneider Hidenori Okamura Antony Crisp Tynchtyk Amatov Milan Dejmek Thomas Carell |
author_sort |
Sidney Becker |
title |
Wet-dry cycles enable the parallel origin of canonical and non-canonical nucleosides by continuous synthesis |
title_short |
Wet-dry cycles enable the parallel origin of canonical and non-canonical nucleosides by continuous synthesis |
title_full |
Wet-dry cycles enable the parallel origin of canonical and non-canonical nucleosides by continuous synthesis |
title_fullStr |
Wet-dry cycles enable the parallel origin of canonical and non-canonical nucleosides by continuous synthesis |
title_full_unstemmed |
Wet-dry cycles enable the parallel origin of canonical and non-canonical nucleosides by continuous synthesis |
title_sort |
wet-dry cycles enable the parallel origin of canonical and non-canonical nucleosides by continuous synthesis |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/f30b47cab3884e568cef79fb2ecc6324 |
work_keys_str_mv |
AT sidneybecker wetdrycyclesenabletheparalleloriginofcanonicalandnoncanonicalnucleosidesbycontinuoussynthesis AT christinaschneider wetdrycyclesenabletheparalleloriginofcanonicalandnoncanonicalnucleosidesbycontinuoussynthesis AT hidenoriokamura wetdrycyclesenabletheparalleloriginofcanonicalandnoncanonicalnucleosidesbycontinuoussynthesis AT antonycrisp wetdrycyclesenabletheparalleloriginofcanonicalandnoncanonicalnucleosidesbycontinuoussynthesis AT tynchtykamatov wetdrycyclesenabletheparalleloriginofcanonicalandnoncanonicalnucleosidesbycontinuoussynthesis AT milandejmek wetdrycyclesenabletheparalleloriginofcanonicalandnoncanonicalnucleosidesbycontinuoussynthesis AT thomascarell wetdrycyclesenabletheparalleloriginofcanonicalandnoncanonicalnucleosidesbycontinuoussynthesis |
_version_ |
1718390569732931584 |