Visual outcome after correcting the refractive error of large pupil patients with wavefront-guided ablation
Mounir A Khalifa,1,2 Waleed A Allam,1,2 Mohamed S Shaheen2,31Ophthalmology Department, Tanta University Eye Hospital, Tanta, Egypt; 2Horus Vision Correction Center, Alexandria, Egypt; 3Ophthalmology Department, Alexandria University, Alexandria, EgyptPurpose: To investigate the efficacy and predicta...
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Dove Medical Press
2012
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oai:doaj.org-article:f30dc81fbb964acd9341bccfaf8910e42021-12-02T08:33:40ZVisual outcome after correcting the refractive error of large pupil patients with wavefront-guided ablation1177-54671177-5483https://doaj.org/article/f30dc81fbb964acd9341bccfaf8910e42012-12-01T00:00:00Zhttp://www.dovepress.com/visual-outcome-after-correcting-the-refractive-error-of-large-pupil-pa-a11661https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Mounir A Khalifa,1,2 Waleed A Allam,1,2 Mohamed S Shaheen2,31Ophthalmology Department, Tanta University Eye Hospital, Tanta, Egypt; 2Horus Vision Correction Center, Alexandria, Egypt; 3Ophthalmology Department, Alexandria University, Alexandria, EgyptPurpose: To investigate the efficacy and predictability of wavefront-guided laser in situ keratomileusis (LASIK) treatments using the iris registration (IR) technology for the correction of refractive errors in patients with large pupils.Setting: Horus Vision Correction Center, Alexandria, Egypt.Methods: Prospective noncomparative study including a total of 52 eyes of 30 consecutive laser refractive correction candidates with large mesopic pupil diameters and myopia or myopic astigmatism. Wavefront-guided LASIK was performed in all cases using the VISX STAR S4 IR excimer laser platform. Visual, refractive, aberrometric and mesopic contrast sensitivity (CS) outcomes were evaluated during a 6-month follow-up.Results: Mean mesopic pupil diameter ranged from 8.0 mm to 9.4 mm. A significant improvement in uncorrected distance visual acuity (UCDVA) (P < 0.01) was found postoperatively, which was consistent with a significant refractive correction (P < 0.01). No significant change was detected in corrected distance visual acuity (CDVA) (P = 0.11). Efficacy index (the ratio of postoperative UCDVA to preoperative CDVA) and safety index (the ratio of postoperative CDVA to preoperative CDVA) were calculated. Mean efficacy and safety indices were 1.06 ± 0.33 and 1.05 ± 0.18, respectively, and 92.31% of eyes had a postoperative spherical equivalent within ±0.50 diopters (D). Manifest refractive spherical equivalent improved significantly (P < 0.05) from a preoperative level of −3.1 ± 1.6 D (range −6.6 to 0 D) to −0.1 ± 0.2 D (range −1.3 to 0.1 D) at 6 months postoperative. No significant changes were found in mesopic CS (P ≥ 0.08), except CS for three cycles/degree, which improved significantly (P = 0.02). Magnitudes of primary coma and trefoil did not change significantly (P ≥ 0.34), with a small but statistically significant increase in primary spherical aberration.Conclusion: Wavefront-guided LASIK provides an effective correction of low to moderate myopia or myopic astigmatism in large pupil patients without deterioration of visual quality.Keywords: large pupil, wavefront, LASIKKhalifa MAAllam WAShaheen MSDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2012, Iss default, Pp 2001-2011 (2012) |
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Ophthalmology RE1-994 |
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Ophthalmology RE1-994 Khalifa MA Allam WA Shaheen MS Visual outcome after correcting the refractive error of large pupil patients with wavefront-guided ablation |
| description |
Mounir A Khalifa,1,2 Waleed A Allam,1,2 Mohamed S Shaheen2,31Ophthalmology Department, Tanta University Eye Hospital, Tanta, Egypt; 2Horus Vision Correction Center, Alexandria, Egypt; 3Ophthalmology Department, Alexandria University, Alexandria, EgyptPurpose: To investigate the efficacy and predictability of wavefront-guided laser in situ keratomileusis (LASIK) treatments using the iris registration (IR) technology for the correction of refractive errors in patients with large pupils.Setting: Horus Vision Correction Center, Alexandria, Egypt.Methods: Prospective noncomparative study including a total of 52 eyes of 30 consecutive laser refractive correction candidates with large mesopic pupil diameters and myopia or myopic astigmatism. Wavefront-guided LASIK was performed in all cases using the VISX STAR S4 IR excimer laser platform. Visual, refractive, aberrometric and mesopic contrast sensitivity (CS) outcomes were evaluated during a 6-month follow-up.Results: Mean mesopic pupil diameter ranged from 8.0 mm to 9.4 mm. A significant improvement in uncorrected distance visual acuity (UCDVA) (P < 0.01) was found postoperatively, which was consistent with a significant refractive correction (P < 0.01). No significant change was detected in corrected distance visual acuity (CDVA) (P = 0.11). Efficacy index (the ratio of postoperative UCDVA to preoperative CDVA) and safety index (the ratio of postoperative CDVA to preoperative CDVA) were calculated. Mean efficacy and safety indices were 1.06 ± 0.33 and 1.05 ± 0.18, respectively, and 92.31% of eyes had a postoperative spherical equivalent within ±0.50 diopters (D). Manifest refractive spherical equivalent improved significantly (P < 0.05) from a preoperative level of −3.1 ± 1.6 D (range −6.6 to 0 D) to −0.1 ± 0.2 D (range −1.3 to 0.1 D) at 6 months postoperative. No significant changes were found in mesopic CS (P ≥ 0.08), except CS for three cycles/degree, which improved significantly (P = 0.02). Magnitudes of primary coma and trefoil did not change significantly (P ≥ 0.34), with a small but statistically significant increase in primary spherical aberration.Conclusion: Wavefront-guided LASIK provides an effective correction of low to moderate myopia or myopic astigmatism in large pupil patients without deterioration of visual quality.Keywords: large pupil, wavefront, LASIK |
| format |
article |
| author |
Khalifa MA Allam WA Shaheen MS |
| author_facet |
Khalifa MA Allam WA Shaheen MS |
| author_sort |
Khalifa MA |
| title |
Visual outcome after correcting the refractive error of large pupil patients with wavefront-guided ablation |
| title_short |
Visual outcome after correcting the refractive error of large pupil patients with wavefront-guided ablation |
| title_full |
Visual outcome after correcting the refractive error of large pupil patients with wavefront-guided ablation |
| title_fullStr |
Visual outcome after correcting the refractive error of large pupil patients with wavefront-guided ablation |
| title_full_unstemmed |
Visual outcome after correcting the refractive error of large pupil patients with wavefront-guided ablation |
| title_sort |
visual outcome after correcting the refractive error of large pupil patients with wavefront-guided ablation |
| publisher |
Dove Medical Press |
| publishDate |
2012 |
| url |
https://doaj.org/article/f30dc81fbb964acd9341bccfaf8910e4 |
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