Chemotaxis-driven delivery of nano-pathogenoids for complete eradication of tumors post-phototherapy

The presence of several biological barriers impede the efficacy of nano-mediated drug delivery for solid cancer therapy. Here, the authors develop a nano-pathogenoid system that targets circulating neutrophils and show that it overcomes these biological barriers and improves tumour targeting and eff...

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Autores principales: Min Li, Shuya Li, Han Zhou, Xinfeng Tang, Yi Wu, Wei Jiang, Zhigang Tian, Xuechang Zhou, Xianzhu Yang, Yucai Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/f31674b4b78a4dd890dc08cb083eb233
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Sumario:The presence of several biological barriers impede the efficacy of nano-mediated drug delivery for solid cancer therapy. Here, the authors develop a nano-pathogenoid system that targets circulating neutrophils and show that it overcomes these biological barriers and improves tumour targeting and efficacy.