Chemotaxis-driven delivery of nano-pathogenoids for complete eradication of tumors post-phototherapy

The presence of several biological barriers impede the efficacy of nano-mediated drug delivery for solid cancer therapy. Here, the authors develop a nano-pathogenoid system that targets circulating neutrophils and show that it overcomes these biological barriers and improves tumour targeting and eff...

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Autores principales: Min Li, Shuya Li, Han Zhou, Xinfeng Tang, Yi Wu, Wei Jiang, Zhigang Tian, Xuechang Zhou, Xianzhu Yang, Yucai Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/f31674b4b78a4dd890dc08cb083eb233
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spelling oai:doaj.org-article:f31674b4b78a4dd890dc08cb083eb2332021-12-02T15:39:16ZChemotaxis-driven delivery of nano-pathogenoids for complete eradication of tumors post-phototherapy10.1038/s41467-020-14963-02041-1723https://doaj.org/article/f31674b4b78a4dd890dc08cb083eb2332020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14963-0https://doaj.org/toc/2041-1723The presence of several biological barriers impede the efficacy of nano-mediated drug delivery for solid cancer therapy. Here, the authors develop a nano-pathogenoid system that targets circulating neutrophils and show that it overcomes these biological barriers and improves tumour targeting and efficacy.Min LiShuya LiHan ZhouXinfeng TangYi WuWei JiangZhigang TianXuechang ZhouXianzhu YangYucai WangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Min Li
Shuya Li
Han Zhou
Xinfeng Tang
Yi Wu
Wei Jiang
Zhigang Tian
Xuechang Zhou
Xianzhu Yang
Yucai Wang
Chemotaxis-driven delivery of nano-pathogenoids for complete eradication of tumors post-phototherapy
description The presence of several biological barriers impede the efficacy of nano-mediated drug delivery for solid cancer therapy. Here, the authors develop a nano-pathogenoid system that targets circulating neutrophils and show that it overcomes these biological barriers and improves tumour targeting and efficacy.
format article
author Min Li
Shuya Li
Han Zhou
Xinfeng Tang
Yi Wu
Wei Jiang
Zhigang Tian
Xuechang Zhou
Xianzhu Yang
Yucai Wang
author_facet Min Li
Shuya Li
Han Zhou
Xinfeng Tang
Yi Wu
Wei Jiang
Zhigang Tian
Xuechang Zhou
Xianzhu Yang
Yucai Wang
author_sort Min Li
title Chemotaxis-driven delivery of nano-pathogenoids for complete eradication of tumors post-phototherapy
title_short Chemotaxis-driven delivery of nano-pathogenoids for complete eradication of tumors post-phototherapy
title_full Chemotaxis-driven delivery of nano-pathogenoids for complete eradication of tumors post-phototherapy
title_fullStr Chemotaxis-driven delivery of nano-pathogenoids for complete eradication of tumors post-phototherapy
title_full_unstemmed Chemotaxis-driven delivery of nano-pathogenoids for complete eradication of tumors post-phototherapy
title_sort chemotaxis-driven delivery of nano-pathogenoids for complete eradication of tumors post-phototherapy
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/f31674b4b78a4dd890dc08cb083eb233
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AT xinfengtang chemotaxisdrivendeliveryofnanopathogenoidsforcompleteeradicationoftumorspostphototherapy
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AT xianzhuyang chemotaxisdrivendeliveryofnanopathogenoidsforcompleteeradicationoftumorspostphototherapy
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