Stimulus dependent diversity and stereotypy in the output of an olfactory functional unit

Mitral/tufted (MT) cells connect to a single glomerulus and receive inputs from sensory neurons expressing the same odorant receptor. Here the authors report that sister MT cells connected to the M72 glomerulus exhibit variable responses to most M72 ligands but respond in a reproducible and stereoty...

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Autores principales: Ezequiel M. Arneodo, Kristina B. Penikis, Neil Rabinowitz, Angela Licata, Annika Cichy, Jingji Zhang, Thomas Bozza, Dmitry Rinberg
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/f32266d57f3345978f6feb96f533479d
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Sumario:Mitral/tufted (MT) cells connect to a single glomerulus and receive inputs from sensory neurons expressing the same odorant receptor. Here the authors report that sister MT cells connected to the M72 glomerulus exhibit variable responses to most M72 ligands but respond in a reproducible and stereotyped way to a high-affinity M72 ligand.