A single mode of population covariation associates brain networks structure and behavior and predicts individual subjects’ age

Brent McPherson and Franco Pestilli build on a large-scale data set from the Cambridge Centre for Aging Neuroscience to examine multivariate relationships between structural brain networks, behavior, and aging in healthy patients aged 18-88 years. They find that the age of individual subjects is pre...

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Bibliographic Details
Main Authors: Brent C. McPherson, Franco Pestilli
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/f32b7141e5c14d31b1666e568dd015dd
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Summary:Brent McPherson and Franco Pestilli build on a large-scale data set from the Cambridge Centre for Aging Neuroscience to examine multivariate relationships between structural brain networks, behavior, and aging in healthy patients aged 18-88 years. They find that the age of individual subjects is predicted by the association between structural connectivity and behavioral measures. They provide a reproducible data processing pipeline at brainlife.io that can be applied to other datasets.