Adherence to the paediatric immunisation schedule in England

Both adequate coverage and adherence to paediatric immunisation schedules are required for optimal protection against vaccine preventable diseases. We studied the timeliness of routine paediatric vaccinations according to the NHS’s immunisation schedule and potential factors of schedule adherence. I...

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Autores principales:	Jorgen Bauwens, Simon de Lusignan, Julian Sherlock, Filipa Ferreira, Nino Künzli, Jan Bonhoeffer
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Adherence Children Immunisation schedule Minors Vaccination Vaccines Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/f32da39470624d318355c622f41588a8
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spelling	oai:doaj.org-article:f32da39470624d318355c622f41588a82021-11-14T04:35:22ZAdherence to the paediatric immunisation schedule in England2590-136210.1016/j.jvacx.2021.100125https://doaj.org/article/f32da39470624d318355c622f41588a82021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2590136221000425https://doaj.org/toc/2590-1362Both adequate coverage and adherence to paediatric immunisation schedules are required for optimal protection against vaccine preventable diseases. We studied the timeliness of routine paediatric vaccinations according to the NHS’s immunisation schedule and potential factors of schedule adherence. Immunisation data was obtained from the Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC). We collected vaccine types, doses, and dates for all routine paediatric vaccines between 2008 and 2018: DTaP/IPV/Hib/HepB, DTaP/IPV/Hib, DTaP/IPV, dTaP/IPV, Td/IPV, MMR, PCV, MenB, MenC, MenACWY, Hib/MenC, RV, HPV. Adherence to the immunisation schedule was calculated for each vaccine and dose. Differences in adherence between genders, NHS regions, and IMD quintiles were analysed. Our study included 6′257′828 vaccinations in 1′005′827 children. Seventy-five percent of first doses were administered within one (for vaccines scheduled in the first year of life) or two months (for vaccines scheduled later in life) following the recommended age, 19% too late and 6% too early. About half of the subsequent doses were given timely. The time between first and second doses was too short for 36% of vaccinations while 13% of second doses were administered too long after the first dose. Third doses were administered timely for 45%, too short for 37%, and too long for 18% of vaccinations. Differences in immunisation schedule adherence between girls and boys were negligible, except for HPV, and differences between the four main NHS regions were small. Overall, immunisation schedule adherence improved slightly with decreasing deprivation according to the Index of Multiple Deprivation. Efforts are required to improve the timeliness of paediatric vaccinations and to assure adequate protection against vaccine preventable diseases. We propose developing a compound measure combining coverage and adherence to provide a better indication of the protection against vaccine preventable diseases in a community.Jorgen BauwensSimon de LusignanJulian SherlockFilipa FerreiraNino KünzliJan BonhoefferElsevierarticleAdherenceChildrenImmunisation scheduleMinorsVaccinationVaccinesImmunologic diseases. AllergyRC581-607ENVaccine: X, Vol 9, Iss , Pp 100125- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Adherence Children Immunisation schedule Minors Vaccination Vaccines Immunologic diseases. Allergy RC581-607
spellingShingle	Adherence Children Immunisation schedule Minors Vaccination Vaccines Immunologic diseases. Allergy RC581-607 Jorgen Bauwens Simon de Lusignan Julian Sherlock Filipa Ferreira Nino Künzli Jan Bonhoeffer Adherence to the paediatric immunisation schedule in England
description	Both adequate coverage and adherence to paediatric immunisation schedules are required for optimal protection against vaccine preventable diseases. We studied the timeliness of routine paediatric vaccinations according to the NHS’s immunisation schedule and potential factors of schedule adherence. Immunisation data was obtained from the Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC). We collected vaccine types, doses, and dates for all routine paediatric vaccines between 2008 and 2018: DTaP/IPV/Hib/HepB, DTaP/IPV/Hib, DTaP/IPV, dTaP/IPV, Td/IPV, MMR, PCV, MenB, MenC, MenACWY, Hib/MenC, RV, HPV. Adherence to the immunisation schedule was calculated for each vaccine and dose. Differences in adherence between genders, NHS regions, and IMD quintiles were analysed. Our study included 6′257′828 vaccinations in 1′005′827 children. Seventy-five percent of first doses were administered within one (for vaccines scheduled in the first year of life) or two months (for vaccines scheduled later in life) following the recommended age, 19% too late and 6% too early. About half of the subsequent doses were given timely. The time between first and second doses was too short for 36% of vaccinations while 13% of second doses were administered too long after the first dose. Third doses were administered timely for 45%, too short for 37%, and too long for 18% of vaccinations. Differences in immunisation schedule adherence between girls and boys were negligible, except for HPV, and differences between the four main NHS regions were small. Overall, immunisation schedule adherence improved slightly with decreasing deprivation according to the Index of Multiple Deprivation. Efforts are required to improve the timeliness of paediatric vaccinations and to assure adequate protection against vaccine preventable diseases. We propose developing a compound measure combining coverage and adherence to provide a better indication of the protection against vaccine preventable diseases in a community.
format	article
author	Jorgen Bauwens Simon de Lusignan Julian Sherlock Filipa Ferreira Nino Künzli Jan Bonhoeffer
author_facet	Jorgen Bauwens Simon de Lusignan Julian Sherlock Filipa Ferreira Nino Künzli Jan Bonhoeffer
author_sort	Jorgen Bauwens
title	Adherence to the paediatric immunisation schedule in England
title_short	Adherence to the paediatric immunisation schedule in England
title_full	Adherence to the paediatric immunisation schedule in England
title_fullStr	Adherence to the paediatric immunisation schedule in England
title_full_unstemmed	Adherence to the paediatric immunisation schedule in England
title_sort	adherence to the paediatric immunisation schedule in england
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/f32da39470624d318355c622f41588a8
work_keys_str_mv	AT jorgenbauwens adherencetothepaediatricimmunisationscheduleinengland AT simondelusignan adherencetothepaediatricimmunisationscheduleinengland AT juliansherlock adherencetothepaediatricimmunisationscheduleinengland AT filipaferreira adherencetothepaediatricimmunisationscheduleinengland AT ninokunzli adherencetothepaediatricimmunisationscheduleinengland AT janbonhoeffer adherencetothepaediatricimmunisationscheduleinengland
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Adherence to the paediatric immunisation schedule in England

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