Pharmacological Inhibition of Wee1 Kinase Selectively Modulates the Voltage-Gated Na<sup>+</sup> Channel 1.2 Macromolecular Complex
Voltage-gated Na<sup>+</sup> (Na<sub>v</sub>) channels are a primary molecular determinant of the action potential (AP). Despite the canonical role of the pore-forming α subunit in conferring this function, protein–protein interactions (PPI) between the Na<sub>v</sub...
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Main Authors: | Nolan M. Dvorak, Cynthia M. Tapia, Timothy J. Baumgartner, Jully Singh, Fernanda Laezza, Aditya K. Singh |
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Format: | article |
Language: | EN |
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MDPI AG
2021
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Online Access: | https://doaj.org/article/f33551dbbfaa43bc9ba2d2846320a3bc |
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