Pharmacological Inhibition of Wee1 Kinase Selectively Modulates the Voltage-Gated Na<sup>+</sup> Channel 1.2 Macromolecular Complex

Voltage-gated Na<sup>+</sup> (Na<sub>v</sub>) channels are a primary molecular determinant of the action potential (AP). Despite the canonical role of the pore-forming α subunit in conferring this function, protein–protein interactions (PPI) between the Na<sub>v</sub...

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Auteurs principaux: Nolan M. Dvorak, Cynthia M. Tapia, Timothy J. Baumgartner, Jully Singh, Fernanda Laezza, Aditya K. Singh
Format: article
Langue:EN
Publié: MDPI AG 2021
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Accès en ligne:https://doaj.org/article/f33551dbbfaa43bc9ba2d2846320a3bc
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