Infertile marriage in patients with diabetes mellitus

Diabetes mellitus affects reproductive function at different levels both in men and women. It disturbs regulation of the hypothalamo-pituitary axisand impairs gonadal endocrine function at the cellular level due to direct effect of acute and/or chronic hyperglycemia, oxidative stress and microvascul...

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Autores principales: Irina Ivanovna Vityazeva, Sergey Vladimirovich Bogolyubov, Irena Adol'fovna Ilovayskaya, Nataliya Petrovna Makarova, Alesya Gennad'evna L'vova
Formato: article
Lenguaje:EN
RU
Publicado: Endocrinology Research Centre 2009
Materias:
art
ecf
Acceso en línea:https://doaj.org/article/f344ff367a074a4bb561140bf7bebaac
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Sumario:Diabetes mellitus affects reproductive function at different levels both in men and women. It disturbs regulation of the hypothalamo-pituitary axisand impairs gonadal endocrine function at the cellular level due to direct effect of acute and/or chronic hyperglycemia, oxidative stress and microvascularcomplications. Moreover, central dysregulation aggravates hormonal disorders. Assisted reproductive technologies (ART) provide a tool for thetreatment of male and female infertility in diabetic patients although many aspects of its application await in-depth studies.