Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis

Being able to predict the therapeutic benefit of disease modifying anti-rheumatic drugs (DMARDs) would be of great benefit and a stepping stone towards personalized medicine. Here the authors use machine learning and lipid mediator mass spectrometry to show specialized pro-resolving mediators are in...

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Autores principales:	Esteban A. Gomez, Romain A. Colas, Patricia R. Souza, Rebecca Hands, Myles J. Lewis, Conrad Bessant, Costantino Pitzalis, Jesmond Dalli
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f34fbd1c4b4842aeb4be2cce58f65db2
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spelling	oai:doaj.org-article:f34fbd1c4b4842aeb4be2cce58f65db22021-12-02T14:42:56ZBlood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis10.1038/s41467-020-19176-z2041-1723https://doaj.org/article/f34fbd1c4b4842aeb4be2cce58f65db22020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19176-zhttps://doaj.org/toc/2041-1723Being able to predict the therapeutic benefit of disease modifying anti-rheumatic drugs (DMARDs) would be of great benefit and a stepping stone towards personalized medicine. Here the authors use machine learning and lipid mediator mass spectrometry to show specialized pro-resolving mediators are indicative of DMARD responsiveness among rheumatoid arthritis patients.Esteban A. GomezRomain A. ColasPatricia R. SouzaRebecca HandsMyles J. LewisConrad BessantCostantino PitzalisJesmond DalliNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Esteban A. Gomez Romain A. Colas Patricia R. Souza Rebecca Hands Myles J. Lewis Conrad Bessant Costantino Pitzalis Jesmond Dalli Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis
description	Being able to predict the therapeutic benefit of disease modifying anti-rheumatic drugs (DMARDs) would be of great benefit and a stepping stone towards personalized medicine. Here the authors use machine learning and lipid mediator mass spectrometry to show specialized pro-resolving mediators are indicative of DMARD responsiveness among rheumatoid arthritis patients.
format	article
author	Esteban A. Gomez Romain A. Colas Patricia R. Souza Rebecca Hands Myles J. Lewis Conrad Bessant Costantino Pitzalis Jesmond Dalli
author_facet	Esteban A. Gomez Romain A. Colas Patricia R. Souza Rebecca Hands Myles J. Lewis Conrad Bessant Costantino Pitzalis Jesmond Dalli
author_sort	Esteban A. Gomez
title	Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis
title_short	Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis
title_full	Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis
title_fullStr	Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis
title_full_unstemmed	Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis
title_sort	blood pro-resolving mediators are linked with synovial pathology and are predictive of dmard responsiveness in rheumatoid arthritis
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/f34fbd1c4b4842aeb4be2cce58f65db2
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Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis

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