Interference with glycosaminoglycan-chemokine interactions with a probe to alter leukocyte recruitment and inflammation in vivo.

Interference with glycosaminoglycan-chemokine interactions with a probe to alter leukocyte recruitment and inflammation in vivo.

In vivo leukocyte recruitment is not fully understood and may result from interactions of chemokines with glycosaminoglycans/GAGs. We previously showed that chlorite-oxidized oxyamylose/COAM binds the neutrophil chemokine GCP-2/CXCL6. Here, mouse chemokine binding by COAM was studied systematically...

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Autores principales: Sandra Li, Ulrika S Pettersson, Bart Hoorelbeke, Elzbieta Kolaczkowska, Katrien Schelfhout, Erik Martens, Paul Kubes, Jo Van Damme, Mia Phillipson, Ghislain Opdenakker
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/f35dc2ff2bf748939bb394b8493d9c42
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