scCODA is a Bayesian model for compositional single-cell data analysis

Imbalance and loss of cell types is a hallmark in many diseases. Still, quantifying compositional changes in scRNAseq data remains challenging. Here the authors present scCODA, a Bayesian model to assess cell type compositions in scRNA-seq data.

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Detalles Bibliográficos
Autores principales: M. Büttner, J. Ostner, C. L. Müller, F. J. Theis, B. Schubert
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/f3602ee8dcdd476385c7f1228e3b7b0c
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Sumario:Imbalance and loss of cell types is a hallmark in many diseases. Still, quantifying compositional changes in scRNAseq data remains challenging. Here the authors present scCODA, a Bayesian model to assess cell type compositions in scRNA-seq data.