scCODA is a Bayesian model for compositional single-cell data analysis

Imbalance and loss of cell types is a hallmark in many diseases. Still, quantifying compositional changes in scRNAseq data remains challenging. Here the authors present scCODA, a Bayesian model to assess cell type compositions in scRNA-seq data.

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Autores principales:	M. Büttner, J. Ostner, C. L. Müller, F. J. Theis, B. Schubert
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f3602ee8dcdd476385c7f1228e3b7b0c
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spelling	oai:doaj.org-article:f3602ee8dcdd476385c7f1228e3b7b0c2021-11-28T12:32:25ZscCODA is a Bayesian model for compositional single-cell data analysis10.1038/s41467-021-27150-62041-1723https://doaj.org/article/f3602ee8dcdd476385c7f1228e3b7b0c2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27150-6https://doaj.org/toc/2041-1723Imbalance and loss of cell types is a hallmark in many diseases. Still, quantifying compositional changes in scRNAseq data remains challenging. Here the authors present scCODA, a Bayesian model to assess cell type compositions in scRNA-seq data.M. BüttnerJ. OstnerC. L. MüllerF. J. TheisB. SchubertNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q M. Büttner J. Ostner C. L. Müller F. J. Theis B. Schubert scCODA is a Bayesian model for compositional single-cell data analysis
description	Imbalance and loss of cell types is a hallmark in many diseases. Still, quantifying compositional changes in scRNAseq data remains challenging. Here the authors present scCODA, a Bayesian model to assess cell type compositions in scRNA-seq data.
format	article
author	M. Büttner J. Ostner C. L. Müller F. J. Theis B. Schubert
author_facet	M. Büttner J. Ostner C. L. Müller F. J. Theis B. Schubert
author_sort	M. Büttner
title	scCODA is a Bayesian model for compositional single-cell data analysis
title_short	scCODA is a Bayesian model for compositional single-cell data analysis
title_full	scCODA is a Bayesian model for compositional single-cell data analysis
title_fullStr	scCODA is a Bayesian model for compositional single-cell data analysis
title_full_unstemmed	scCODA is a Bayesian model for compositional single-cell data analysis
title_sort	sccoda is a bayesian model for compositional single-cell data analysis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/f3602ee8dcdd476385c7f1228e3b7b0c
work_keys_str_mv	AT mbuttner sccodaisabayesianmodelforcompositionalsinglecelldataanalysis AT jostner sccodaisabayesianmodelforcompositionalsinglecelldataanalysis AT clmuller sccodaisabayesianmodelforcompositionalsinglecelldataanalysis AT fjtheis sccodaisabayesianmodelforcompositionalsinglecelldataanalysis AT bschubert sccodaisabayesianmodelforcompositionalsinglecelldataanalysis
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scCODA is a Bayesian model for compositional single-cell data analysis

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