Obesity, Even in the Metabolically Healthy, Increases the Risk of Poor Physical Performance: A Cross-Sectional Study of Older People in a Chinese Community

Weibo Ma,1,* Yuewen Liu,1,* Ning Wu,1 Hui Zhang,1 Peipei Han,1 Feng Wang,1 Jingru Wang,1 Fandi Xie,2 Shumeng Niu,2 Hao Hu,2 Chenyu Zhang,1 Nuo Chen,1 Yichen Zhang,1 Qi Guo,1 Ying Yu1 1Department of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences, Shanghai, People&rsq...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Ma W, Liu Y, Wu N, Zhang H, Han P, Wang F, Wang J, Xie F, Niu S, Hu H, Zhang C, Chen N, Zhang Y, Guo Q, Yu Y
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2021
Materias:
Acceso en línea:https://doaj.org/article/f3715f137aad4aac9ea258fa2fb4fada
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:f3715f137aad4aac9ea258fa2fb4fada
record_format dspace
spelling oai:doaj.org-article:f3715f137aad4aac9ea258fa2fb4fada2021-12-02T17:30:30ZObesity, Even in the Metabolically Healthy, Increases the Risk of Poor Physical Performance: A Cross-Sectional Study of Older People in a Chinese Community1178-1998https://doaj.org/article/f3715f137aad4aac9ea258fa2fb4fada2021-04-01T00:00:00Zhttps://www.dovepress.com/obesity-even-in-the-metabolically-healthy-increases-the-risk-of-poor-p-peer-reviewed-fulltext-article-CIAhttps://doaj.org/toc/1178-1998Weibo Ma,1,* Yuewen Liu,1,* Ning Wu,1 Hui Zhang,1 Peipei Han,1 Feng Wang,1 Jingru Wang,1 Fandi Xie,2 Shumeng Niu,2 Hao Hu,2 Chenyu Zhang,1 Nuo Chen,1 Yichen Zhang,1 Qi Guo,1 Ying Yu1 1Department of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences, Shanghai, People’s Republic of China; 2Department of Clinical Laboratory Center, Shanghai Jiangwan Hospital, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qi GuoDepartment of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences, No. 279 Zhouzhu Road, Pudong New Area, Shanghai, 201318, People’s Republic of ChinaTel +86-21-8333-6977Fax +86-21-8333-6977Email guoqijp@gmail.comYing Yu Email yuying@sumhs.edu.cnObjective: We examined the association between obesity and physical performance under different metabolic status.Methods: The sample included 1395 Chinese community-dwelling participants (mean age, 71.88 ± 5.87 years; 40.9% men). Being metabolically healthy was defined as having the presence of < 3 of 5 components of metabolic syndrome (MetS); obesity was defined as having a BMI > 28 kg/m2. Participants were divided into four groups based on BMI (non-obese/obese) and metabolic health (healthy/unhealthy). Physical performance was measured by grip strength, 4-m walking speed, and the timed up and go test (TUGT).Results: After multiple adjustments, compared with metabolically healthy non-obese group, the metabolically unhealthy obese group showed lower relative grip strength, lower 4-m walking speed, and higher TUGT (P all < 0.05), and only relative grip strength of the metabolically healthy obese group was significantly lower than that of metabolically healthy non-obese (P < 0.01). Relative grip strength was negatively associated with impaired fasting glucose (β = − 0.071), elevated triglycerides (β = − 0.062), abdominal obesity (β = − 0.230) and general obesity (β = − 0.225) (P all < 0.01). Walking speed and TUGT were only associated with general obesity, rather than other metabolic components. The associations of MetS with physical performance were mainly driven by abdominal obesity.Conclusion: Even in those who are metabolically healthy, obesity (especially general obesity) increases the risk of poor physical performance. Elderly people with general obesity and MetS, whether in combination or alone, have an increased risk of muscle dysfunction, and that combination produces a higher risk of impaired mobility.Keywords: metabolic health, obesity, physical performance, grip strength, 4-m walking speed, TUGTMa WLiu YWu NZhang HHan PWang FWang JXie FNiu SHu HZhang CChen NZhang YGuo QYu YDove Medical Pressarticlemetabolic healthobesityphysical performancegrip strength4-m walking speedtugtGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 16, Pp 697-706 (2021)
institution DOAJ
collection DOAJ
language EN
topic metabolic health
obesity
physical performance
grip strength
4-m walking speed
tugt
Geriatrics
RC952-954.6
spellingShingle metabolic health
obesity
physical performance
grip strength
4-m walking speed
tugt
Geriatrics
RC952-954.6
Ma W
Liu Y
Wu N
Zhang H
Han P
Wang F
Wang J
Xie F
Niu S
Hu H
Zhang C
Chen N
Zhang Y
Guo Q
Yu Y
Obesity, Even in the Metabolically Healthy, Increases the Risk of Poor Physical Performance: A Cross-Sectional Study of Older People in a Chinese Community
description Weibo Ma,1,* Yuewen Liu,1,* Ning Wu,1 Hui Zhang,1 Peipei Han,1 Feng Wang,1 Jingru Wang,1 Fandi Xie,2 Shumeng Niu,2 Hao Hu,2 Chenyu Zhang,1 Nuo Chen,1 Yichen Zhang,1 Qi Guo,1 Ying Yu1 1Department of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences, Shanghai, People’s Republic of China; 2Department of Clinical Laboratory Center, Shanghai Jiangwan Hospital, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qi GuoDepartment of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences, No. 279 Zhouzhu Road, Pudong New Area, Shanghai, 201318, People’s Republic of ChinaTel +86-21-8333-6977Fax +86-21-8333-6977Email guoqijp@gmail.comYing Yu Email yuying@sumhs.edu.cnObjective: We examined the association between obesity and physical performance under different metabolic status.Methods: The sample included 1395 Chinese community-dwelling participants (mean age, 71.88 ± 5.87 years; 40.9% men). Being metabolically healthy was defined as having the presence of < 3 of 5 components of metabolic syndrome (MetS); obesity was defined as having a BMI > 28 kg/m2. Participants were divided into four groups based on BMI (non-obese/obese) and metabolic health (healthy/unhealthy). Physical performance was measured by grip strength, 4-m walking speed, and the timed up and go test (TUGT).Results: After multiple adjustments, compared with metabolically healthy non-obese group, the metabolically unhealthy obese group showed lower relative grip strength, lower 4-m walking speed, and higher TUGT (P all < 0.05), and only relative grip strength of the metabolically healthy obese group was significantly lower than that of metabolically healthy non-obese (P < 0.01). Relative grip strength was negatively associated with impaired fasting glucose (β = − 0.071), elevated triglycerides (β = − 0.062), abdominal obesity (β = − 0.230) and general obesity (β = − 0.225) (P all < 0.01). Walking speed and TUGT were only associated with general obesity, rather than other metabolic components. The associations of MetS with physical performance were mainly driven by abdominal obesity.Conclusion: Even in those who are metabolically healthy, obesity (especially general obesity) increases the risk of poor physical performance. Elderly people with general obesity and MetS, whether in combination or alone, have an increased risk of muscle dysfunction, and that combination produces a higher risk of impaired mobility.Keywords: metabolic health, obesity, physical performance, grip strength, 4-m walking speed, TUGT
format article
author Ma W
Liu Y
Wu N
Zhang H
Han P
Wang F
Wang J
Xie F
Niu S
Hu H
Zhang C
Chen N
Zhang Y
Guo Q
Yu Y
author_facet Ma W
Liu Y
Wu N
Zhang H
Han P
Wang F
Wang J
Xie F
Niu S
Hu H
Zhang C
Chen N
Zhang Y
Guo Q
Yu Y
author_sort Ma W
title Obesity, Even in the Metabolically Healthy, Increases the Risk of Poor Physical Performance: A Cross-Sectional Study of Older People in a Chinese Community
title_short Obesity, Even in the Metabolically Healthy, Increases the Risk of Poor Physical Performance: A Cross-Sectional Study of Older People in a Chinese Community
title_full Obesity, Even in the Metabolically Healthy, Increases the Risk of Poor Physical Performance: A Cross-Sectional Study of Older People in a Chinese Community
title_fullStr Obesity, Even in the Metabolically Healthy, Increases the Risk of Poor Physical Performance: A Cross-Sectional Study of Older People in a Chinese Community
title_full_unstemmed Obesity, Even in the Metabolically Healthy, Increases the Risk of Poor Physical Performance: A Cross-Sectional Study of Older People in a Chinese Community
title_sort obesity, even in the metabolically healthy, increases the risk of poor physical performance: a cross-sectional study of older people in a chinese community
publisher Dove Medical Press
publishDate 2021
url https://doaj.org/article/f3715f137aad4aac9ea258fa2fb4fada
work_keys_str_mv AT maw obesityeveninthemetabolicallyhealthyincreasestheriskofpoorphysicalperformanceacrosssectionalstudyofolderpeopleinachinesecommunity
AT liuy obesityeveninthemetabolicallyhealthyincreasestheriskofpoorphysicalperformanceacrosssectionalstudyofolderpeopleinachinesecommunity
AT wun obesityeveninthemetabolicallyhealthyincreasestheriskofpoorphysicalperformanceacrosssectionalstudyofolderpeopleinachinesecommunity
AT zhangh obesityeveninthemetabolicallyhealthyincreasestheriskofpoorphysicalperformanceacrosssectionalstudyofolderpeopleinachinesecommunity
AT hanp obesityeveninthemetabolicallyhealthyincreasestheriskofpoorphysicalperformanceacrosssectionalstudyofolderpeopleinachinesecommunity
AT wangf obesityeveninthemetabolicallyhealthyincreasestheriskofpoorphysicalperformanceacrosssectionalstudyofolderpeopleinachinesecommunity
AT wangj obesityeveninthemetabolicallyhealthyincreasestheriskofpoorphysicalperformanceacrosssectionalstudyofolderpeopleinachinesecommunity
AT xief obesityeveninthemetabolicallyhealthyincreasestheriskofpoorphysicalperformanceacrosssectionalstudyofolderpeopleinachinesecommunity
AT nius obesityeveninthemetabolicallyhealthyincreasestheriskofpoorphysicalperformanceacrosssectionalstudyofolderpeopleinachinesecommunity
AT huh obesityeveninthemetabolicallyhealthyincreasestheriskofpoorphysicalperformanceacrosssectionalstudyofolderpeopleinachinesecommunity
AT zhangc obesityeveninthemetabolicallyhealthyincreasestheriskofpoorphysicalperformanceacrosssectionalstudyofolderpeopleinachinesecommunity
AT chenn obesityeveninthemetabolicallyhealthyincreasestheriskofpoorphysicalperformanceacrosssectionalstudyofolderpeopleinachinesecommunity
AT zhangy obesityeveninthemetabolicallyhealthyincreasestheriskofpoorphysicalperformanceacrosssectionalstudyofolderpeopleinachinesecommunity
AT guoq obesityeveninthemetabolicallyhealthyincreasestheriskofpoorphysicalperformanceacrosssectionalstudyofolderpeopleinachinesecommunity
AT yuy obesityeveninthemetabolicallyhealthyincreasestheriskofpoorphysicalperformanceacrosssectionalstudyofolderpeopleinachinesecommunity
_version_ 1718380765400530944