Vaccine-associated feline sarcoma: current perspectives

Corey F Saba Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA, USA Abstract: Feline injection site sarcomas (FISS; also known as vaccine-associated sarcomas) have been recognized for >20 years. Although uncommon, these...

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Autor principal:	Saba CF
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	injection site sarcoma cat cancer oncology Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/f374647f8b614968aea6bab9e5f37657
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spelling	oai:doaj.org-article:f374647f8b614968aea6bab9e5f376572021-12-02T01:19:21ZVaccine-associated feline sarcoma: current perspectives2230-2034https://doaj.org/article/f374647f8b614968aea6bab9e5f376572017-01-01T00:00:00Zhttps://www.dovepress.com/vaccine-associated-feline-sarcoma-current-perspectives-peer-reviewed-article-VMRRhttps://doaj.org/toc/2230-2034Corey F Saba Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA, USA Abstract: Feline injection site sarcomas (FISS; also known as vaccine-associated sarcomas) have been recognized for >20 years. Although uncommon, these tumors are iatrogenic, and vaccination against rabies and feline leukemia virus is perhaps the most common inciting cause. The exact etiopathogenesis is unknown, but it is widely accepted that inflammation induced by vaccines or other injections likely plays a critical role in tumor development. Injection site sarcomas are extremely locally invasive. Multimodal therapy, incorporating combinations of surgery, radiation therapy, and sometimes chemotherapy or immunotherapy, is recommended. However, tumor recurrences are common even with aggressive treatment, and many cats with FISS ultimately succumb to this devastating disease. While vaccination protocols play an important role in the management and control of infectious disease, veterinarians must be diligent in following established vaccination guidelines to minimize individual patient risk of FISS development. Early tumor detection and client education are also vital in the successful treatment of FISS. Keywords: injection site sarcoma, cat, cancer, oncologySaba CFDove Medical Pressarticleinjection site sarcomacatcanceroncologyVeterinary medicineSF600-1100ENVeterinary Medicine: Research and Reports, Vol Volume 8, Pp 13-20 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	injection site sarcoma cat cancer oncology Veterinary medicine SF600-1100
spellingShingle	injection site sarcoma cat cancer oncology Veterinary medicine SF600-1100 Saba CF Vaccine-associated feline sarcoma: current perspectives
description	Corey F Saba Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA, USA Abstract: Feline injection site sarcomas (FISS; also known as vaccine-associated sarcomas) have been recognized for >20 years. Although uncommon, these tumors are iatrogenic, and vaccination against rabies and feline leukemia virus is perhaps the most common inciting cause. The exact etiopathogenesis is unknown, but it is widely accepted that inflammation induced by vaccines or other injections likely plays a critical role in tumor development. Injection site sarcomas are extremely locally invasive. Multimodal therapy, incorporating combinations of surgery, radiation therapy, and sometimes chemotherapy or immunotherapy, is recommended. However, tumor recurrences are common even with aggressive treatment, and many cats with FISS ultimately succumb to this devastating disease. While vaccination protocols play an important role in the management and control of infectious disease, veterinarians must be diligent in following established vaccination guidelines to minimize individual patient risk of FISS development. Early tumor detection and client education are also vital in the successful treatment of FISS. Keywords: injection site sarcoma, cat, cancer, oncology
format	article
author	Saba CF
author_facet	Saba CF
author_sort	Saba CF
title	Vaccine-associated feline sarcoma: current perspectives
title_short	Vaccine-associated feline sarcoma: current perspectives
title_full	Vaccine-associated feline sarcoma: current perspectives
title_fullStr	Vaccine-associated feline sarcoma: current perspectives
title_full_unstemmed	Vaccine-associated feline sarcoma: current perspectives
title_sort	vaccine-associated feline sarcoma: current perspectives
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/f374647f8b614968aea6bab9e5f37657
work_keys_str_mv	AT sabacf vaccineassociatedfelinesarcomacurrentperspectives
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Vaccine-associated feline sarcoma: current perspectives

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