Deriving mechanisms responsible for the lack of correlation between hypoxia and acidity in solid tumors.

Deriving mechanisms responsible for the lack of correlation between hypoxia and acidity in solid tumors.

Hypoxia and acidity are two main microenvironmental factors intimately associated with solid tumors and play critical roles in tumor growth and metastasis. The experimental results of Helmlinger and colleagues (Nature Medicine 3, 177, 1997) provide evidence of a lack of correlation between these fac...

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Autores principales: Hamid R Molavian, Mohammad Kohandel, Michael Milosevic, Sivabal Sivaloganathan
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
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Science
Q
Acceso en línea:https://doaj.org/article/f37e7081acc343a980c4edbe539612c2
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