ROLE OF COMBINED KETOCONAZOLE AND TAMSULOSIN IN SUCCESSFUL TRIAL OF VOIDING WITHOUT CATHETER (TWOC) IN PATIENTS WITH ACUTE URINARY RETENTION DUE TO BENIGN PROSTATIC OBSTRUCTION

Objective: To compare the frequency of patients with successful Trial of voiding without catheter (TWOC) after acute urinary retention secondary to benign prostatic hyperplasia in patients taking ketoconazole and tamsulosin vs tamsulosin alone. Study Design: A randomized controlled trial. Pla...

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Autores principales:	Muhammad Asim, Syed Farhan Ahmed, Muhammad Sajid Ali, Imran Memon, Waqas Memon, Muhammad Rashid, Kiran Abbas, Moiz Ahmed
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2020
Materias:	tamsulosin ketoconazole acute urinary retention trial without catheter benign prostatic hyperplasia Medicine R Medicine (General) R5-920
Acceso en línea:	https://doi.org/10.51253/pafmj.v70i6.3913 https://doaj.org/article/f382075539304f50b98d2e77f34aa313
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spelling	oai:doaj.org-article:f382075539304f50b98d2e77f34aa3132021-12-02T17:16:15ZROLE OF COMBINED KETOCONAZOLE AND TAMSULOSIN IN SUCCESSFUL TRIAL OF VOIDING WITHOUT CATHETER (TWOC) IN PATIENTS WITH ACUTE URINARY RETENTION DUE TO BENIGN PROSTATIC OBSTRUCTIONhttps://doi.org/10.51253/pafmj.v70i6.39130030-96482411-8842https://doaj.org/article/f382075539304f50b98d2e77f34aa3132020-12-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/3913https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To compare the frequency of patients with successful Trial of voiding without catheter (TWOC) after acute urinary retention secondary to benign prostatic hyperplasia in patients taking ketoconazole and tamsulosin vs tamsulosin alone. Study Design: A randomized controlled trial. Place and Duration: The current study was conducted at Urology Ward, Liaquat National Hospital, Pakistan for a period of six months. Methodology: A total of 162 patients presenting with acute urinary retention were divided into two groups. Group A received tamsulosin 0.4mg OD and ketoconazole 200mg while Group B received tamsulosin and placebo. Trial of voiding without a catheter was induced after one week of medication. SPSS version 20 was used for data compilation and analysis. Results: In Group-A, 85.2% of patients were able to void as compared to group B, where only 74.1% of patients were able to void (p<0.05). Successful trial of voiding without catheter was observed in 79.0% and 60.5% in patients of Group-A and Group-B respectively. The association of successful TWOC with the two study groups was found significant (p=0.010). Conclusion: TWOC in men catheterized for AUR due to BPH was significantly more successful if treated in a combination of ketoconazole and tamsulosin as compared to tamsulosin only.Muhammad AsimSyed Farhan AhmedMuhammad Sajid AliImran MemonWaqas MemonMuhammad RashidKiran AbbasMoiz AhmedArmy Medical College Rawalpindiarticletamsulosinketoconazoleacute urinary retentiontrial without catheterbenign prostatic hyperplasiaMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 70, Iss 6, Pp 1723-1727 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	tamsulosin ketoconazole acute urinary retention trial without catheter benign prostatic hyperplasia Medicine R Medicine (General) R5-920
spellingShingle	tamsulosin ketoconazole acute urinary retention trial without catheter benign prostatic hyperplasia Medicine R Medicine (General) R5-920 Muhammad Asim Syed Farhan Ahmed Muhammad Sajid Ali Imran Memon Waqas Memon Muhammad Rashid Kiran Abbas Moiz Ahmed ROLE OF COMBINED KETOCONAZOLE AND TAMSULOSIN IN SUCCESSFUL TRIAL OF VOIDING WITHOUT CATHETER (TWOC) IN PATIENTS WITH ACUTE URINARY RETENTION DUE TO BENIGN PROSTATIC OBSTRUCTION
description	Objective: To compare the frequency of patients with successful Trial of voiding without catheter (TWOC) after acute urinary retention secondary to benign prostatic hyperplasia in patients taking ketoconazole and tamsulosin vs tamsulosin alone. Study Design: A randomized controlled trial. Place and Duration: The current study was conducted at Urology Ward, Liaquat National Hospital, Pakistan for a period of six months. Methodology: A total of 162 patients presenting with acute urinary retention were divided into two groups. Group A received tamsulosin 0.4mg OD and ketoconazole 200mg while Group B received tamsulosin and placebo. Trial of voiding without a catheter was induced after one week of medication. SPSS version 20 was used for data compilation and analysis. Results: In Group-A, 85.2% of patients were able to void as compared to group B, where only 74.1% of patients were able to void (p<0.05). Successful trial of voiding without catheter was observed in 79.0% and 60.5% in patients of Group-A and Group-B respectively. The association of successful TWOC with the two study groups was found significant (p=0.010). Conclusion: TWOC in men catheterized for AUR due to BPH was significantly more successful if treated in a combination of ketoconazole and tamsulosin as compared to tamsulosin only.
format	article
author	Muhammad Asim Syed Farhan Ahmed Muhammad Sajid Ali Imran Memon Waqas Memon Muhammad Rashid Kiran Abbas Moiz Ahmed
author_facet	Muhammad Asim Syed Farhan Ahmed Muhammad Sajid Ali Imran Memon Waqas Memon Muhammad Rashid Kiran Abbas Moiz Ahmed
author_sort	Muhammad Asim
title	ROLE OF COMBINED KETOCONAZOLE AND TAMSULOSIN IN SUCCESSFUL TRIAL OF VOIDING WITHOUT CATHETER (TWOC) IN PATIENTS WITH ACUTE URINARY RETENTION DUE TO BENIGN PROSTATIC OBSTRUCTION
title_short	ROLE OF COMBINED KETOCONAZOLE AND TAMSULOSIN IN SUCCESSFUL TRIAL OF VOIDING WITHOUT CATHETER (TWOC) IN PATIENTS WITH ACUTE URINARY RETENTION DUE TO BENIGN PROSTATIC OBSTRUCTION
title_full	ROLE OF COMBINED KETOCONAZOLE AND TAMSULOSIN IN SUCCESSFUL TRIAL OF VOIDING WITHOUT CATHETER (TWOC) IN PATIENTS WITH ACUTE URINARY RETENTION DUE TO BENIGN PROSTATIC OBSTRUCTION
title_fullStr	ROLE OF COMBINED KETOCONAZOLE AND TAMSULOSIN IN SUCCESSFUL TRIAL OF VOIDING WITHOUT CATHETER (TWOC) IN PATIENTS WITH ACUTE URINARY RETENTION DUE TO BENIGN PROSTATIC OBSTRUCTION
title_full_unstemmed	ROLE OF COMBINED KETOCONAZOLE AND TAMSULOSIN IN SUCCESSFUL TRIAL OF VOIDING WITHOUT CATHETER (TWOC) IN PATIENTS WITH ACUTE URINARY RETENTION DUE TO BENIGN PROSTATIC OBSTRUCTION
title_sort	role of combined ketoconazole and tamsulosin in successful trial of voiding without catheter (twoc) in patients with acute urinary retention due to benign prostatic obstruction
publisher	Army Medical College Rawalpindi
publishDate	2020
url	https://doi.org/10.51253/pafmj.v70i6.3913 https://doaj.org/article/f382075539304f50b98d2e77f34aa313
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ROLE OF COMBINED KETOCONAZOLE AND TAMSULOSIN IN SUCCESSFUL TRIAL OF VOIDING WITHOUT CATHETER (TWOC) IN PATIENTS WITH ACUTE URINARY RETENTION DUE TO BENIGN PROSTATIC OBSTRUCTION

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