Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation

Snail is a transcription factor that induces epithelial-mesenchymal transition. Here the authors show that, in the mesenchymal subtype of ovarian cancer, Snail expression promotes tumorigenesis by inducing immune evasion through CXCR2-ligands-mediated recruitment of myeloid-derived suppressor cells.

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Autores principales:	Mana Taki, Kaoru Abiko, Tsukasa Baba, Junzo Hamanishi, Ken Yamaguchi, Ryusuke Murakami, Koji Yamanoi, Naoki Horikawa, Yuko Hosoe, Eijiro Nakamura, Aiko Sugiyama, Masaki Mandai, Ikuo Konishi, Noriomi Matsumura
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f38abf5181994159babcc334fe37c767
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:f38abf5181994159babcc334fe37c7672021-12-02T16:49:19ZSnail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation10.1038/s41467-018-03966-72041-1723https://doaj.org/article/f38abf5181994159babcc334fe37c7672018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03966-7https://doaj.org/toc/2041-1723Snail is a transcription factor that induces epithelial-mesenchymal transition. Here the authors show that, in the mesenchymal subtype of ovarian cancer, Snail expression promotes tumorigenesis by inducing immune evasion through CXCR2-ligands-mediated recruitment of myeloid-derived suppressor cells.Mana TakiKaoru AbikoTsukasa BabaJunzo HamanishiKen YamaguchiRyusuke MurakamiKoji YamanoiNaoki HorikawaYuko HosoeEijiro NakamuraAiko SugiyamaMasaki MandaiIkuo KonishiNoriomi MatsumuraNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mana Taki Kaoru Abiko Tsukasa Baba Junzo Hamanishi Ken Yamaguchi Ryusuke Murakami Koji Yamanoi Naoki Horikawa Yuko Hosoe Eijiro Nakamura Aiko Sugiyama Masaki Mandai Ikuo Konishi Noriomi Matsumura Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation
description	Snail is a transcription factor that induces epithelial-mesenchymal transition. Here the authors show that, in the mesenchymal subtype of ovarian cancer, Snail expression promotes tumorigenesis by inducing immune evasion through CXCR2-ligands-mediated recruitment of myeloid-derived suppressor cells.
format	article
author	Mana Taki Kaoru Abiko Tsukasa Baba Junzo Hamanishi Ken Yamaguchi Ryusuke Murakami Koji Yamanoi Naoki Horikawa Yuko Hosoe Eijiro Nakamura Aiko Sugiyama Masaki Mandai Ikuo Konishi Noriomi Matsumura
author_facet	Mana Taki Kaoru Abiko Tsukasa Baba Junzo Hamanishi Ken Yamaguchi Ryusuke Murakami Koji Yamanoi Naoki Horikawa Yuko Hosoe Eijiro Nakamura Aiko Sugiyama Masaki Mandai Ikuo Konishi Noriomi Matsumura
author_sort	Mana Taki
title	Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation
title_short	Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation
title_full	Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation
title_fullStr	Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation
title_full_unstemmed	Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation
title_sort	snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via cxcr2 ligand upregulation
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/f38abf5181994159babcc334fe37c767
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Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation

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