Immunological and inflammatory profiles in mild and severe cases of COVID-19

Immunological and inflammatory profiles in mild and severe cases of COVID-19

Immunophenotyping of patients with COVID-19 is ongoing, but much remains to be learned. Here the authors analyze 41 hospitalized patients with COVID-19 and show a higher degree of lymphopenia in various immune cell subsets as well as cytotoxicity and T cell inhibitory marker expression in severe cas...

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Main Authors: Jin-Wen Song, Chao Zhang, Xing Fan, Fan-Ping Meng, Zhe Xu, Peng Xia, Wen-Jing Cao, Tao Yang, Xiao-Peng Dai, Si-Yu Wang, Ruo-Nan Xu, Tian-Jun Jiang, Wen-Gang Li, Da-Wei Zhang, Peng Zhao, Ming Shi, Chiara Agrati, Giuseppe Ippolito, Markus Maeurer, Alimuddin Zumla, Fu-Sheng Wang, Ji-Yuan Zhang
Format: article
Language:EN
Published: Nature Portfolio 2020
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Science
Q
Online Access:https://doaj.org/article/f394b906bb734d0da841b3a0209b27e6
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Summary:Immunophenotyping of patients with COVID-19 is ongoing, but much remains to be learned. Here the authors analyze 41 hospitalized patients with COVID-19 and show a higher degree of lymphopenia in various immune cell subsets as well as cytotoxicity and T cell inhibitory marker expression in severe cases compared with mild.

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