Immunological and inflammatory profiles in mild and severe cases of COVID-19
Immunophenotyping of patients with COVID-19 is ongoing, but much remains to be learned. Here the authors analyze 41 hospitalized patients with COVID-19 and show a higher degree of lymphopenia in various immune cell subsets as well as cytotoxicity and T cell inhibitory marker expression in severe cas...
Guardado en:
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/f394b906bb734d0da841b3a0209b27e6 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:f394b906bb734d0da841b3a0209b27e6 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:f394b906bb734d0da841b3a0209b27e62021-12-02T16:14:49ZImmunological and inflammatory profiles in mild and severe cases of COVID-1910.1038/s41467-020-17240-22041-1723https://doaj.org/article/f394b906bb734d0da841b3a0209b27e62020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17240-2https://doaj.org/toc/2041-1723Immunophenotyping of patients with COVID-19 is ongoing, but much remains to be learned. Here the authors analyze 41 hospitalized patients with COVID-19 and show a higher degree of lymphopenia in various immune cell subsets as well as cytotoxicity and T cell inhibitory marker expression in severe cases compared with mild.Jin-Wen SongChao ZhangXing FanFan-Ping MengZhe XuPeng XiaWen-Jing CaoTao YangXiao-Peng DaiSi-Yu WangRuo-Nan XuTian-Jun JiangWen-Gang LiDa-Wei ZhangPeng ZhaoMing ShiChiara AgratiGiuseppe IppolitoMarkus MaeurerAlimuddin ZumlaFu-Sheng WangJi-Yuan ZhangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Jin-Wen Song Chao Zhang Xing Fan Fan-Ping Meng Zhe Xu Peng Xia Wen-Jing Cao Tao Yang Xiao-Peng Dai Si-Yu Wang Ruo-Nan Xu Tian-Jun Jiang Wen-Gang Li Da-Wei Zhang Peng Zhao Ming Shi Chiara Agrati Giuseppe Ippolito Markus Maeurer Alimuddin Zumla Fu-Sheng Wang Ji-Yuan Zhang Immunological and inflammatory profiles in mild and severe cases of COVID-19 |
description |
Immunophenotyping of patients with COVID-19 is ongoing, but much remains to be learned. Here the authors analyze 41 hospitalized patients with COVID-19 and show a higher degree of lymphopenia in various immune cell subsets as well as cytotoxicity and T cell inhibitory marker expression in severe cases compared with mild. |
format |
article |
author |
Jin-Wen Song Chao Zhang Xing Fan Fan-Ping Meng Zhe Xu Peng Xia Wen-Jing Cao Tao Yang Xiao-Peng Dai Si-Yu Wang Ruo-Nan Xu Tian-Jun Jiang Wen-Gang Li Da-Wei Zhang Peng Zhao Ming Shi Chiara Agrati Giuseppe Ippolito Markus Maeurer Alimuddin Zumla Fu-Sheng Wang Ji-Yuan Zhang |
author_facet |
Jin-Wen Song Chao Zhang Xing Fan Fan-Ping Meng Zhe Xu Peng Xia Wen-Jing Cao Tao Yang Xiao-Peng Dai Si-Yu Wang Ruo-Nan Xu Tian-Jun Jiang Wen-Gang Li Da-Wei Zhang Peng Zhao Ming Shi Chiara Agrati Giuseppe Ippolito Markus Maeurer Alimuddin Zumla Fu-Sheng Wang Ji-Yuan Zhang |
author_sort |
Jin-Wen Song |
title |
Immunological and inflammatory profiles in mild and severe cases of COVID-19 |
title_short |
Immunological and inflammatory profiles in mild and severe cases of COVID-19 |
title_full |
Immunological and inflammatory profiles in mild and severe cases of COVID-19 |
title_fullStr |
Immunological and inflammatory profiles in mild and severe cases of COVID-19 |
title_full_unstemmed |
Immunological and inflammatory profiles in mild and severe cases of COVID-19 |
title_sort |
immunological and inflammatory profiles in mild and severe cases of covid-19 |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/f394b906bb734d0da841b3a0209b27e6 |
work_keys_str_mv |
AT jinwensong immunologicalandinflammatoryprofilesinmildandseverecasesofcovid19 AT chaozhang immunologicalandinflammatoryprofilesinmildandseverecasesofcovid19 AT xingfan immunologicalandinflammatoryprofilesinmildandseverecasesofcovid19 AT fanpingmeng immunologicalandinflammatoryprofilesinmildandseverecasesofcovid19 AT zhexu immunologicalandinflammatoryprofilesinmildandseverecasesofcovid19 AT pengxia immunologicalandinflammatoryprofilesinmildandseverecasesofcovid19 AT wenjingcao immunologicalandinflammatoryprofilesinmildandseverecasesofcovid19 AT taoyang immunologicalandinflammatoryprofilesinmildandseverecasesofcovid19 AT xiaopengdai immunologicalandinflammatoryprofilesinmildandseverecasesofcovid19 AT siyuwang immunologicalandinflammatoryprofilesinmildandseverecasesofcovid19 AT ruonanxu immunologicalandinflammatoryprofilesinmildandseverecasesofcovid19 AT tianjunjiang immunologicalandinflammatoryprofilesinmildandseverecasesofcovid19 AT wengangli immunologicalandinflammatoryprofilesinmildandseverecasesofcovid19 AT daweizhang immunologicalandinflammatoryprofilesinmildandseverecasesofcovid19 AT pengzhao immunologicalandinflammatoryprofilesinmildandseverecasesofcovid19 AT mingshi immunologicalandinflammatoryprofilesinmildandseverecasesofcovid19 AT chiaraagrati immunologicalandinflammatoryprofilesinmildandseverecasesofcovid19 AT giuseppeippolito immunologicalandinflammatoryprofilesinmildandseverecasesofcovid19 AT markusmaeurer immunologicalandinflammatoryprofilesinmildandseverecasesofcovid19 AT alimuddinzumla immunologicalandinflammatoryprofilesinmildandseverecasesofcovid19 AT fushengwang immunologicalandinflammatoryprofilesinmildandseverecasesofcovid19 AT jiyuanzhang immunologicalandinflammatoryprofilesinmildandseverecasesofcovid19 |
_version_ |
1718384327091290112 |