Immunological and inflammatory profiles in mild and severe cases of COVID-19

Immunophenotyping of patients with COVID-19 is ongoing, but much remains to be learned. Here the authors analyze 41 hospitalized patients with COVID-19 and show a higher degree of lymphopenia in various immune cell subsets as well as cytotoxicity and T cell inhibitory marker expression in severe cas...

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Autores principales: Jin-Wen Song, Chao Zhang, Xing Fan, Fan-Ping Meng, Zhe Xu, Peng Xia, Wen-Jing Cao, Tao Yang, Xiao-Peng Dai, Si-Yu Wang, Ruo-Nan Xu, Tian-Jun Jiang, Wen-Gang Li, Da-Wei Zhang, Peng Zhao, Ming Shi, Chiara Agrati, Giuseppe Ippolito, Markus Maeurer, Alimuddin Zumla, Fu-Sheng Wang, Ji-Yuan Zhang
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/f394b906bb734d0da841b3a0209b27e6
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spelling oai:doaj.org-article:f394b906bb734d0da841b3a0209b27e62021-12-02T16:14:49ZImmunological and inflammatory profiles in mild and severe cases of COVID-1910.1038/s41467-020-17240-22041-1723https://doaj.org/article/f394b906bb734d0da841b3a0209b27e62020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17240-2https://doaj.org/toc/2041-1723Immunophenotyping of patients with COVID-19 is ongoing, but much remains to be learned. Here the authors analyze 41 hospitalized patients with COVID-19 and show a higher degree of lymphopenia in various immune cell subsets as well as cytotoxicity and T cell inhibitory marker expression in severe cases compared with mild.Jin-Wen SongChao ZhangXing FanFan-Ping MengZhe XuPeng XiaWen-Jing CaoTao YangXiao-Peng DaiSi-Yu WangRuo-Nan XuTian-Jun JiangWen-Gang LiDa-Wei ZhangPeng ZhaoMing ShiChiara AgratiGiuseppe IppolitoMarkus MaeurerAlimuddin ZumlaFu-Sheng WangJi-Yuan ZhangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jin-Wen Song
Chao Zhang
Xing Fan
Fan-Ping Meng
Zhe Xu
Peng Xia
Wen-Jing Cao
Tao Yang
Xiao-Peng Dai
Si-Yu Wang
Ruo-Nan Xu
Tian-Jun Jiang
Wen-Gang Li
Da-Wei Zhang
Peng Zhao
Ming Shi
Chiara Agrati
Giuseppe Ippolito
Markus Maeurer
Alimuddin Zumla
Fu-Sheng Wang
Ji-Yuan Zhang
Immunological and inflammatory profiles in mild and severe cases of COVID-19
description Immunophenotyping of patients with COVID-19 is ongoing, but much remains to be learned. Here the authors analyze 41 hospitalized patients with COVID-19 and show a higher degree of lymphopenia in various immune cell subsets as well as cytotoxicity and T cell inhibitory marker expression in severe cases compared with mild.
format article
author Jin-Wen Song
Chao Zhang
Xing Fan
Fan-Ping Meng
Zhe Xu
Peng Xia
Wen-Jing Cao
Tao Yang
Xiao-Peng Dai
Si-Yu Wang
Ruo-Nan Xu
Tian-Jun Jiang
Wen-Gang Li
Da-Wei Zhang
Peng Zhao
Ming Shi
Chiara Agrati
Giuseppe Ippolito
Markus Maeurer
Alimuddin Zumla
Fu-Sheng Wang
Ji-Yuan Zhang
author_facet Jin-Wen Song
Chao Zhang
Xing Fan
Fan-Ping Meng
Zhe Xu
Peng Xia
Wen-Jing Cao
Tao Yang
Xiao-Peng Dai
Si-Yu Wang
Ruo-Nan Xu
Tian-Jun Jiang
Wen-Gang Li
Da-Wei Zhang
Peng Zhao
Ming Shi
Chiara Agrati
Giuseppe Ippolito
Markus Maeurer
Alimuddin Zumla
Fu-Sheng Wang
Ji-Yuan Zhang
author_sort Jin-Wen Song
title Immunological and inflammatory profiles in mild and severe cases of COVID-19
title_short Immunological and inflammatory profiles in mild and severe cases of COVID-19
title_full Immunological and inflammatory profiles in mild and severe cases of COVID-19
title_fullStr Immunological and inflammatory profiles in mild and severe cases of COVID-19
title_full_unstemmed Immunological and inflammatory profiles in mild and severe cases of COVID-19
title_sort immunological and inflammatory profiles in mild and severe cases of covid-19
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/f394b906bb734d0da841b3a0209b27e6
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