Normalized Cardiac Structure and Function in COVID-19 Survivors Late After Recovery

Background: Coronavirus disease 2019 can result in myocardial injury in the acute phase. However, information on the late cardiac consequences of coronavirus disease 2019 (COVID-19) is limited.Methods: We conducted a prospective observational cohort study to investigate the late cardiac consequences...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Yi-Ping Gao, Wei Zhou, Pei-Na Huang, Hong-Yun Liu, Xiao-Jun Bi, Ying Zhu, Jie Sun, Qiao-Ying Tang, Li Li, Jun Zhang, Rui-Ying Sun, Xue-Qing Cheng, Ya-Ni Liu, You-Bin Deng
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	COVID-19 speckle tracking echocardiography myocardial strain NT-proBNP troponin Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/f396dc0fb707493084eabb0e5755579a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f396dc0fb707493084eabb0e5755579a
record_format	dspace
spelling	oai:doaj.org-article:f396dc0fb707493084eabb0e5755579a2021-12-01T13:15:40ZNormalized Cardiac Structure and Function in COVID-19 Survivors Late After Recovery2297-055X10.3389/fcvm.2021.756790https://doaj.org/article/f396dc0fb707493084eabb0e5755579a2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fcvm.2021.756790/fullhttps://doaj.org/toc/2297-055XBackground: Coronavirus disease 2019 can result in myocardial injury in the acute phase. However, information on the late cardiac consequences of coronavirus disease 2019 (COVID-19) is limited.Methods: We conducted a prospective observational cohort study to investigate the late cardiac consequences of COVID-19. Standard echocardiography and myocardial strain assessment were performed, and cardiac blood biomarkers were tested in 86 COVID-19 survivors 327 days (IQR 318–337 days) after recovery. Comparisons were made with 28 age-matched and sex-matched healthy controls and 30 risk factor-matched patients.Results: There were no significant differences in all echocardiographic structural and functional parameters, including left ventricular (LV) global longitudinal strain, right ventricular (RV) longitudinal strain, LV end-diastolic volume, RV dimension, and the ratio of peak early velocity in mitral inflow to peak early diastolic velocity in the septal mitral annulus (E/e') among COVID-19 survivors, healthy controls and risk factor-matched controls. Even 26 patients with myocardial injury at admission did not have any echocardiographic structural and functional abnormalities. There were no significant differences among the three groups with respect to serum concentrations of N-terminal pro-B-type natriuretic peptide (NT-proBNP) and high-sensitivity cardiac troponin I (cTnI).Conclusion: This study showed that COVID-19 survivors, including those with myocardial injury at admission and those with severe and critical types of illness, do not have any echocardiographic evidence of cardiac structural and functional abnormalities 327 days after diagnosis.Yi-Ping GaoWei ZhouPei-Na HuangHong-Yun LiuXiao-Jun BiYing ZhuJie SunQiao-Ying TangLi LiJun ZhangRui-Ying SunXue-Qing ChengYa-Ni LiuYou-Bin DengFrontiers Media S.A.articleCOVID-19speckle tracking echocardiographymyocardial strainNT-proBNPtroponinDiseases of the circulatory (Cardiovascular) systemRC666-701ENFrontiers in Cardiovascular Medicine, Vol 8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	COVID-19 speckle tracking echocardiography myocardial strain NT-proBNP troponin Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	COVID-19 speckle tracking echocardiography myocardial strain NT-proBNP troponin Diseases of the circulatory (Cardiovascular) system RC666-701 Yi-Ping Gao Wei Zhou Pei-Na Huang Hong-Yun Liu Xiao-Jun Bi Ying Zhu Jie Sun Qiao-Ying Tang Li Li Jun Zhang Rui-Ying Sun Xue-Qing Cheng Ya-Ni Liu You-Bin Deng Normalized Cardiac Structure and Function in COVID-19 Survivors Late After Recovery
description	Background: Coronavirus disease 2019 can result in myocardial injury in the acute phase. However, information on the late cardiac consequences of coronavirus disease 2019 (COVID-19) is limited.Methods: We conducted a prospective observational cohort study to investigate the late cardiac consequences of COVID-19. Standard echocardiography and myocardial strain assessment were performed, and cardiac blood biomarkers were tested in 86 COVID-19 survivors 327 days (IQR 318–337 days) after recovery. Comparisons were made with 28 age-matched and sex-matched healthy controls and 30 risk factor-matched patients.Results: There were no significant differences in all echocardiographic structural and functional parameters, including left ventricular (LV) global longitudinal strain, right ventricular (RV) longitudinal strain, LV end-diastolic volume, RV dimension, and the ratio of peak early velocity in mitral inflow to peak early diastolic velocity in the septal mitral annulus (E/e') among COVID-19 survivors, healthy controls and risk factor-matched controls. Even 26 patients with myocardial injury at admission did not have any echocardiographic structural and functional abnormalities. There were no significant differences among the three groups with respect to serum concentrations of N-terminal pro-B-type natriuretic peptide (NT-proBNP) and high-sensitivity cardiac troponin I (cTnI).Conclusion: This study showed that COVID-19 survivors, including those with myocardial injury at admission and those with severe and critical types of illness, do not have any echocardiographic evidence of cardiac structural and functional abnormalities 327 days after diagnosis.
format	article
author	Yi-Ping Gao Wei Zhou Pei-Na Huang Hong-Yun Liu Xiao-Jun Bi Ying Zhu Jie Sun Qiao-Ying Tang Li Li Jun Zhang Rui-Ying Sun Xue-Qing Cheng Ya-Ni Liu You-Bin Deng
author_facet	Yi-Ping Gao Wei Zhou Pei-Na Huang Hong-Yun Liu Xiao-Jun Bi Ying Zhu Jie Sun Qiao-Ying Tang Li Li Jun Zhang Rui-Ying Sun Xue-Qing Cheng Ya-Ni Liu You-Bin Deng
author_sort	Yi-Ping Gao
title	Normalized Cardiac Structure and Function in COVID-19 Survivors Late After Recovery
title_short	Normalized Cardiac Structure and Function in COVID-19 Survivors Late After Recovery
title_full	Normalized Cardiac Structure and Function in COVID-19 Survivors Late After Recovery
title_fullStr	Normalized Cardiac Structure and Function in COVID-19 Survivors Late After Recovery
title_full_unstemmed	Normalized Cardiac Structure and Function in COVID-19 Survivors Late After Recovery
title_sort	normalized cardiac structure and function in covid-19 survivors late after recovery
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/f396dc0fb707493084eabb0e5755579a
work_keys_str_mv	AT yipinggao normalizedcardiacstructureandfunctionincovid19survivorslateafterrecovery AT weizhou normalizedcardiacstructureandfunctionincovid19survivorslateafterrecovery AT peinahuang normalizedcardiacstructureandfunctionincovid19survivorslateafterrecovery AT hongyunliu normalizedcardiacstructureandfunctionincovid19survivorslateafterrecovery AT xiaojunbi normalizedcardiacstructureandfunctionincovid19survivorslateafterrecovery AT yingzhu normalizedcardiacstructureandfunctionincovid19survivorslateafterrecovery AT jiesun normalizedcardiacstructureandfunctionincovid19survivorslateafterrecovery AT qiaoyingtang normalizedcardiacstructureandfunctionincovid19survivorslateafterrecovery AT lili normalizedcardiacstructureandfunctionincovid19survivorslateafterrecovery AT junzhang normalizedcardiacstructureandfunctionincovid19survivorslateafterrecovery AT ruiyingsun normalizedcardiacstructureandfunctionincovid19survivorslateafterrecovery AT xueqingcheng normalizedcardiacstructureandfunctionincovid19survivorslateafterrecovery AT yaniliu normalizedcardiacstructureandfunctionincovid19survivorslateafterrecovery AT youbindeng normalizedcardiacstructureandfunctionincovid19survivorslateafterrecovery
_version_	1718405151577866240

Normalized Cardiac Structure and Function in COVID-19 Survivors Late After Recovery

Ejemplares similares