Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells

Single-cell metabolomics can offer deep insights into the metabolic reprogramming that accompanies disease states. Here, the authors use Raman spectro-microscopy for non-invasive metabolite analysis and identification of druggable metabolic susceptibilities in single live melanoma cells.

Guardado en:

Detalles Bibliográficos
Autores principales:	Jiajun Du, Yapeng Su, Chenxi Qian, Dan Yuan, Kun Miao, Dongkwan Lee, Alphonsus H. C. Ng, Reto S. Wijker, Antoni Ribas, Raphael D. Levine, James R. Heath, Lu Wei
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f39a0cf1dee44ceca635fab34b78f662
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f39a0cf1dee44ceca635fab34b78f662
record_format	dspace
spelling	oai:doaj.org-article:f39a0cf1dee44ceca635fab34b78f6622021-12-02T18:14:01ZRaman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells10.1038/s41467-020-18376-x2041-1723https://doaj.org/article/f39a0cf1dee44ceca635fab34b78f6622020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18376-xhttps://doaj.org/toc/2041-1723Single-cell metabolomics can offer deep insights into the metabolic reprogramming that accompanies disease states. Here, the authors use Raman spectro-microscopy for non-invasive metabolite analysis and identification of druggable metabolic susceptibilities in single live melanoma cells.Jiajun DuYapeng SuChenxi QianDan YuanKun MiaoDongkwan LeeAlphonsus H. C. NgReto S. WijkerAntoni RibasRaphael D. LevineJames R. HeathLu WeiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jiajun Du Yapeng Su Chenxi Qian Dan Yuan Kun Miao Dongkwan Lee Alphonsus H. C. Ng Reto S. Wijker Antoni Ribas Raphael D. Levine James R. Heath Lu Wei Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells
description	Single-cell metabolomics can offer deep insights into the metabolic reprogramming that accompanies disease states. Here, the authors use Raman spectro-microscopy for non-invasive metabolite analysis and identification of druggable metabolic susceptibilities in single live melanoma cells.
format	article
author	Jiajun Du Yapeng Su Chenxi Qian Dan Yuan Kun Miao Dongkwan Lee Alphonsus H. C. Ng Reto S. Wijker Antoni Ribas Raphael D. Levine James R. Heath Lu Wei
author_facet	Jiajun Du Yapeng Su Chenxi Qian Dan Yuan Kun Miao Dongkwan Lee Alphonsus H. C. Ng Reto S. Wijker Antoni Ribas Raphael D. Levine James R. Heath Lu Wei
author_sort	Jiajun Du
title	Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells
title_short	Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells
title_full	Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells
title_fullStr	Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells
title_full_unstemmed	Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells
title_sort	raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/f39a0cf1dee44ceca635fab34b78f662
work_keys_str_mv	AT jiajundu ramanguidedsubcellularpharmacometabolomicsformetastaticmelanomacells AT yapengsu ramanguidedsubcellularpharmacometabolomicsformetastaticmelanomacells AT chenxiqian ramanguidedsubcellularpharmacometabolomicsformetastaticmelanomacells AT danyuan ramanguidedsubcellularpharmacometabolomicsformetastaticmelanomacells AT kunmiao ramanguidedsubcellularpharmacometabolomicsformetastaticmelanomacells AT dongkwanlee ramanguidedsubcellularpharmacometabolomicsformetastaticmelanomacells AT alphonsushcng ramanguidedsubcellularpharmacometabolomicsformetastaticmelanomacells AT retoswijker ramanguidedsubcellularpharmacometabolomicsformetastaticmelanomacells AT antoniribas ramanguidedsubcellularpharmacometabolomicsformetastaticmelanomacells AT raphaeldlevine ramanguidedsubcellularpharmacometabolomicsformetastaticmelanomacells AT jamesrheath ramanguidedsubcellularpharmacometabolomicsformetastaticmelanomacells AT luwei ramanguidedsubcellularpharmacometabolomicsformetastaticmelanomacells
_version_	1718378487778115584

Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells

Ejemplares similares