Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells

Single-cell metabolomics can offer deep insights into the metabolic reprogramming that accompanies disease states. Here, the authors use Raman spectro-microscopy for non-invasive metabolite analysis and identification of druggable metabolic susceptibilities in single live melanoma cells.

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Auteurs principaux:	Jiajun Du, Yapeng Su, Chenxi Qian, Dan Yuan, Kun Miao, Dongkwan Lee, Alphonsus H. C. Ng, Reto S. Wijker, Antoni Ribas, Raphael D. Levine, James R. Heath, Lu Wei
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2020
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/f39a0cf1dee44ceca635fab34b78f662
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spelling	oai:doaj.org-article:f39a0cf1dee44ceca635fab34b78f6622021-12-02T18:14:01ZRaman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells10.1038/s41467-020-18376-x2041-1723https://doaj.org/article/f39a0cf1dee44ceca635fab34b78f6622020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18376-xhttps://doaj.org/toc/2041-1723Single-cell metabolomics can offer deep insights into the metabolic reprogramming that accompanies disease states. Here, the authors use Raman spectro-microscopy for non-invasive metabolite analysis and identification of druggable metabolic susceptibilities in single live melanoma cells.Jiajun DuYapeng SuChenxi QianDan YuanKun MiaoDongkwan LeeAlphonsus H. C. NgReto S. WijkerAntoni RibasRaphael D. LevineJames R. HeathLu WeiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jiajun Du Yapeng Su Chenxi Qian Dan Yuan Kun Miao Dongkwan Lee Alphonsus H. C. Ng Reto S. Wijker Antoni Ribas Raphael D. Levine James R. Heath Lu Wei Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells
description	Single-cell metabolomics can offer deep insights into the metabolic reprogramming that accompanies disease states. Here, the authors use Raman spectro-microscopy for non-invasive metabolite analysis and identification of druggable metabolic susceptibilities in single live melanoma cells.
format	article
author	Jiajun Du Yapeng Su Chenxi Qian Dan Yuan Kun Miao Dongkwan Lee Alphonsus H. C. Ng Reto S. Wijker Antoni Ribas Raphael D. Levine James R. Heath Lu Wei
author_facet	Jiajun Du Yapeng Su Chenxi Qian Dan Yuan Kun Miao Dongkwan Lee Alphonsus H. C. Ng Reto S. Wijker Antoni Ribas Raphael D. Levine James R. Heath Lu Wei
author_sort	Jiajun Du
title	Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells
title_short	Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells
title_full	Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells
title_fullStr	Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells
title_full_unstemmed	Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells
title_sort	raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/f39a0cf1dee44ceca635fab34b78f662
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Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells

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