Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells

Single-cell metabolomics can offer deep insights into the metabolic reprogramming that accompanies disease states. Here, the authors use Raman spectro-microscopy for non-invasive metabolite analysis and identification of druggable metabolic susceptibilities in single live melanoma cells.

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Bibliographic Details
Main Authors: Jiajun Du, Yapeng Su, Chenxi Qian, Dan Yuan, Kun Miao, Dongkwan Lee, Alphonsus H. C. Ng, Reto S. Wijker, Antoni Ribas, Raphael D. Levine, James R. Heath, Lu Wei
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/f39a0cf1dee44ceca635fab34b78f662
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