Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4

Nontyphoidal Salmonella (NTS) is a major cause of bacteraemia in children and HIV-infected adults in Africa. Here, Gilchrist et al. conduct a genome-wide association study and show that genetic variation in STAT4 is a determinant of NTS in Kenyan and Malawian children.

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Autores principales:	James J. Gilchrist, Anna Rautanen, Benjamin P. Fairfax, Tara C. Mills, Vivek Naranbhai, Holly Trochet, Matti Pirinen, Esther Muthumbi, Salim Mwarumba, Patricia Njuguna, Neema Mturi, Chisomo L. Msefula, Esther N. Gondwe, Jenny M. MacLennan, Stephen J. Chapman, Malcolm E. Molyneux, Julian C. Knight, Chris C. A. Spencer, Thomas N. Williams, Calman A. MacLennan, J. Anthony G. Scott, Adrian V. S. Hill
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f39fdec2fbbb4ab0bac55463ac8b21f7
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spelling	oai:doaj.org-article:f39fdec2fbbb4ab0bac55463ac8b21f72021-12-02T15:33:42ZRisk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT410.1038/s41467-017-02398-z2041-1723https://doaj.org/article/f39fdec2fbbb4ab0bac55463ac8b21f72018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02398-zhttps://doaj.org/toc/2041-1723Nontyphoidal Salmonella (NTS) is a major cause of bacteraemia in children and HIV-infected adults in Africa. Here, Gilchrist et al. conduct a genome-wide association study and show that genetic variation in STAT4 is a determinant of NTS in Kenyan and Malawian children.James J. GilchristAnna RautanenBenjamin P. FairfaxTara C. MillsVivek NaranbhaiHolly TrochetMatti PirinenEsther MuthumbiSalim MwarumbaPatricia NjugunaNeema MturiChisomo L. MsefulaEsther N. GondweJenny M. MacLennanStephen J. ChapmanMalcolm E. MolyneuxJulian C. KnightChris C. A. SpencerThomas N. WilliamsCalman A. MacLennanJ. Anthony G. ScottAdrian V. S. HillNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q James J. Gilchrist Anna Rautanen Benjamin P. Fairfax Tara C. Mills Vivek Naranbhai Holly Trochet Matti Pirinen Esther Muthumbi Salim Mwarumba Patricia Njuguna Neema Mturi Chisomo L. Msefula Esther N. Gondwe Jenny M. MacLennan Stephen J. Chapman Malcolm E. Molyneux Julian C. Knight Chris C. A. Spencer Thomas N. Williams Calman A. MacLennan J. Anthony G. Scott Adrian V. S. Hill Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4
description	Nontyphoidal Salmonella (NTS) is a major cause of bacteraemia in children and HIV-infected adults in Africa. Here, Gilchrist et al. conduct a genome-wide association study and show that genetic variation in STAT4 is a determinant of NTS in Kenyan and Malawian children.
format	article
author	James J. Gilchrist Anna Rautanen Benjamin P. Fairfax Tara C. Mills Vivek Naranbhai Holly Trochet Matti Pirinen Esther Muthumbi Salim Mwarumba Patricia Njuguna Neema Mturi Chisomo L. Msefula Esther N. Gondwe Jenny M. MacLennan Stephen J. Chapman Malcolm E. Molyneux Julian C. Knight Chris C. A. Spencer Thomas N. Williams Calman A. MacLennan J. Anthony G. Scott Adrian V. S. Hill
author_facet	James J. Gilchrist Anna Rautanen Benjamin P. Fairfax Tara C. Mills Vivek Naranbhai Holly Trochet Matti Pirinen Esther Muthumbi Salim Mwarumba Patricia Njuguna Neema Mturi Chisomo L. Msefula Esther N. Gondwe Jenny M. MacLennan Stephen J. Chapman Malcolm E. Molyneux Julian C. Knight Chris C. A. Spencer Thomas N. Williams Calman A. MacLennan J. Anthony G. Scott Adrian V. S. Hill
author_sort	James J. Gilchrist
title	Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4
title_short	Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4
title_full	Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4
title_fullStr	Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4
title_full_unstemmed	Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4
title_sort	risk of nontyphoidal salmonella bacteraemia in african children is modified by stat4
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/f39fdec2fbbb4ab0bac55463ac8b21f7
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Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4

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