Early redox activities modulate Xenopus tail regeneration

Reactive oxygen species (ROS) and hypoxia-inducible factors (HIF) mediate regeneration but how is unclear. Here, the authors use an optic-based probe (‘optrode’) to monitor oxygen (O2) during Xenopus tail regeneration, identifying crosstalk between O2 influx, ROS production, and HIF-1α stabilization...

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Autores principales: Fernando Ferreira, VijayKrishna Raghunathan, Guillaume Luxardi, Kan Zhu, Min Zhao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/f3ab9ec838cc49768feff3e1cc2f2ef9
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