Enhanced derivation of human pluripotent stem cell-derived cortical glutamatergic neurons by a small molecule

Enhanced derivation of human pluripotent stem cell-derived cortical glutamatergic neurons by a small molecule

Abstract Human pluripotent stem cells (hPSCs) play important role in studying the function of human glutamatergic neurons and related disease pathogenesis. However, the current hPSC-derived cortical system produced a significant number of inhibitory GABAergic neurons that reduced the purity of excit...

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Autores principales: Shi-Ying Cao, Yao Hu, Cheng Chen, Fang Yuan, Min Xu, Qi Li, Kai-Heng Fang, Yaoyu Chen, Yan Liu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/f3af8a0054d549e5bf87dcd461c40c7d
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