UNUSUAL METABOLIC COMPLICATIONS OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA: HYPERCALCEMIA, HYPERAMONEMIA, LACTIC ASIDOSIS

Case report: We present three children with precursor B acute lymphoblastic leukemia (ALL). The first one had malignancy associated hypercalcemia at diagnosis. The second one experienced hyperamonemia during induction. Both of them had been treated successfully. The last one had refractory leukemia...

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Main Authors:	Dilek Kaçar, Aslı Turgutoğlu Yılmaz, Ayça Koca Yozgat, Neşe Yaralı
Format:	article
Language:	EN
Published:	Elsevier 2021
Subjects:	Diseases of the blood and blood-forming organs RC633-647.5
Online Access:	https://doaj.org/article/f3b136323ea847eeae39d3625e82d192
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spelling	oai:doaj.org-article:f3b136323ea847eeae39d3625e82d1922021-11-10T04:38:29ZUNUSUAL METABOLIC COMPLICATIONS OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA: HYPERCALCEMIA, HYPERAMONEMIA, LACTIC ASIDOSIS2531-137910.1016/j.htct.2021.10.1079https://doaj.org/article/f3b136323ea847eeae39d3625e82d1922021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2531137921012268https://doaj.org/toc/2531-1379Case report: We present three children with precursor B acute lymphoblastic leukemia (ALL). The first one had malignancy associated hypercalcemia at diagnosis. The second one experienced hyperamonemia during induction. Both of them had been treated successfully. The last one had refractory leukemia and died because of lactic acidosis due to extensive infiltration of the liver by tumor cells. The rare but potential fatal metabolic complications of ALL needs high clinical suspicion and prompt treatment.Dilek KaçarAslı Turgutoğlu YılmazAyça Koca YozgatNeşe YaralıElsevierarticleDiseases of the blood and blood-forming organsRC633-647.5ENHematology, Transfusion and Cell Therapy, Vol 43, Iss , Pp S59- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the blood and blood-forming organs RC633-647.5
spellingShingle	Diseases of the blood and blood-forming organs RC633-647.5 Dilek Kaçar Aslı Turgutoğlu Yılmaz Ayça Koca Yozgat Neşe Yaralı UNUSUAL METABOLIC COMPLICATIONS OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA: HYPERCALCEMIA, HYPERAMONEMIA, LACTIC ASIDOSIS
description	Case report: We present three children with precursor B acute lymphoblastic leukemia (ALL). The first one had malignancy associated hypercalcemia at diagnosis. The second one experienced hyperamonemia during induction. Both of them had been treated successfully. The last one had refractory leukemia and died because of lactic acidosis due to extensive infiltration of the liver by tumor cells. The rare but potential fatal metabolic complications of ALL needs high clinical suspicion and prompt treatment.
format	article
author	Dilek Kaçar Aslı Turgutoğlu Yılmaz Ayça Koca Yozgat Neşe Yaralı
author_facet	Dilek Kaçar Aslı Turgutoğlu Yılmaz Ayça Koca Yozgat Neşe Yaralı
author_sort	Dilek Kaçar
title	UNUSUAL METABOLIC COMPLICATIONS OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA: HYPERCALCEMIA, HYPERAMONEMIA, LACTIC ASIDOSIS
title_short	UNUSUAL METABOLIC COMPLICATIONS OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA: HYPERCALCEMIA, HYPERAMONEMIA, LACTIC ASIDOSIS
title_full	UNUSUAL METABOLIC COMPLICATIONS OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA: HYPERCALCEMIA, HYPERAMONEMIA, LACTIC ASIDOSIS
title_fullStr	UNUSUAL METABOLIC COMPLICATIONS OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA: HYPERCALCEMIA, HYPERAMONEMIA, LACTIC ASIDOSIS
title_full_unstemmed	UNUSUAL METABOLIC COMPLICATIONS OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA: HYPERCALCEMIA, HYPERAMONEMIA, LACTIC ASIDOSIS
title_sort	unusual metabolic complications of childhood acute lymphoblastic leukemia: hypercalcemia, hyperamonemia, lactic asidosis
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/f3b136323ea847eeae39d3625e82d192
work_keys_str_mv	AT dilekkacar unusualmetaboliccomplicationsofchildhoodacutelymphoblasticleukemiahypercalcemiahyperamonemialacticasidosis AT aslıturgutogluyılmaz unusualmetaboliccomplicationsofchildhoodacutelymphoblasticleukemiahypercalcemiahyperamonemialacticasidosis AT aycakocayozgat unusualmetaboliccomplicationsofchildhoodacutelymphoblasticleukemiahypercalcemiahyperamonemialacticasidosis AT neseyaralı unusualmetaboliccomplicationsofchildhoodacutelymphoblasticleukemiahypercalcemiahyperamonemialacticasidosis
_version_	1718440613092786176

UNUSUAL METABOLIC COMPLICATIONS OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA: HYPERCALCEMIA, HYPERAMONEMIA, LACTIC ASIDOSIS

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