Quantification of lactate from various metabolic pathways and quantification issues of lactate isotopologues and isotopmers
Abstract 13C-labeled glucose combined with chromatography and mass spectrometry enables us to decipher the percentage of lactate generated from various metabolic pathways. We showed that lactate derived from glycolysis, pentose phosphate pathway, Krebs cycle, and other sources accounted for 82–90%,...
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Main Authors: | Wei Zhang, Cheng Guo, Kezhi Jiang, Minfeng Ying, Xun Hu |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
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Online Access: | https://doaj.org/article/f3c9ce25c6a34fad9c17cdf43f83d2f0 |
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