The soft mechanical signature of glial scars in the central nervous system

Glial scars are thought to provide a biochemical and mechanical barrier to neuronal regeneration post-injury, but the mechanical properties of the scars have not been studied in detail. Here the authors perform atomic force microscopy measurements of glial scars from the injured rat cortex and spina...

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Autores principales:	Emad Moeendarbary, Isabell P. Weber, Graham K. Sheridan, David E. Koser, Sara Soleman, Barbara Haenzi, Elizabeth J. Bradbury, James Fawcett, Kristian Franze
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f3d2bdc08870472282335918d0b3b16c
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spelling	oai:doaj.org-article:f3d2bdc08870472282335918d0b3b16c2021-12-02T17:06:00ZThe soft mechanical signature of glial scars in the central nervous system10.1038/ncomms147872041-1723https://doaj.org/article/f3d2bdc08870472282335918d0b3b16c2017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14787https://doaj.org/toc/2041-1723Glial scars are thought to provide a biochemical and mechanical barrier to neuronal regeneration post-injury, but the mechanical properties of the scars have not been studied in detail. Here the authors perform atomic force microscopy measurements of glial scars from the injured rat cortex and spinal cord, and find that brain tissue softens in response to the injury.Emad MoeendarbaryIsabell P. WeberGraham K. SheridanDavid E. KoserSara SolemanBarbara HaenziElizabeth J. BradburyJames FawcettKristian FranzeNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Emad Moeendarbary Isabell P. Weber Graham K. Sheridan David E. Koser Sara Soleman Barbara Haenzi Elizabeth J. Bradbury James Fawcett Kristian Franze The soft mechanical signature of glial scars in the central nervous system
description	Glial scars are thought to provide a biochemical and mechanical barrier to neuronal regeneration post-injury, but the mechanical properties of the scars have not been studied in detail. Here the authors perform atomic force microscopy measurements of glial scars from the injured rat cortex and spinal cord, and find that brain tissue softens in response to the injury.
format	article
author	Emad Moeendarbary Isabell P. Weber Graham K. Sheridan David E. Koser Sara Soleman Barbara Haenzi Elizabeth J. Bradbury James Fawcett Kristian Franze
author_facet	Emad Moeendarbary Isabell P. Weber Graham K. Sheridan David E. Koser Sara Soleman Barbara Haenzi Elizabeth J. Bradbury James Fawcett Kristian Franze
author_sort	Emad Moeendarbary
title	The soft mechanical signature of glial scars in the central nervous system
title_short	The soft mechanical signature of glial scars in the central nervous system
title_full	The soft mechanical signature of glial scars in the central nervous system
title_fullStr	The soft mechanical signature of glial scars in the central nervous system
title_full_unstemmed	The soft mechanical signature of glial scars in the central nervous system
title_sort	soft mechanical signature of glial scars in the central nervous system
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/f3d2bdc08870472282335918d0b3b16c
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The soft mechanical signature of glial scars in the central nervous system

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