Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling

The molecular mechanisms regulating adult neural stem/progenitor cell differentiation following damage of the central nervous system are unclear. Here, the authors show that fibrinogen is a regulator of the adult neural stem/progenitor cell switch from neurogenesis to astrogenesis in a model of stro...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Lauriane Pous, Sachin S. Deshpande, Suvra Nath, Szilvia Mezey, Subash C. Malik, Sebastian Schildge, Christian Bohrer, Könül Topp, Dietmar Pfeifer, Francisco Fernández-Klett, Soroush Doostkam, Dennis K. Galanakis, Verdon Taylor, Katerina Akassoglou, Christian Schachtrup
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f3d973f0777646bfaf11ff6400d0b81e
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f3d973f0777646bfaf11ff6400d0b81e
record_format	dspace
spelling	oai:doaj.org-article:f3d973f0777646bfaf11ff6400d0b81e2021-12-02T17:32:13ZFibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling10.1038/s41467-020-14466-y2041-1723https://doaj.org/article/f3d973f0777646bfaf11ff6400d0b81e2020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14466-yhttps://doaj.org/toc/2041-1723The molecular mechanisms regulating adult neural stem/progenitor cell differentiation following damage of the central nervous system are unclear. Here, the authors show that fibrinogen is a regulator of the adult neural stem/progenitor cell switch from neurogenesis to astrogenesis in a model of strokeLauriane PousSachin S. DeshpandeSuvra NathSzilvia MezeySubash C. MalikSebastian SchildgeChristian BohrerKönül ToppDietmar PfeiferFrancisco Fernández-KlettSoroush DoostkamDennis K. GalanakisVerdon TaylorKaterina AkassoglouChristian SchachtrupNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Lauriane Pous Sachin S. Deshpande Suvra Nath Szilvia Mezey Subash C. Malik Sebastian Schildge Christian Bohrer Könül Topp Dietmar Pfeifer Francisco Fernández-Klett Soroush Doostkam Dennis K. Galanakis Verdon Taylor Katerina Akassoglou Christian Schachtrup Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling
description	The molecular mechanisms regulating adult neural stem/progenitor cell differentiation following damage of the central nervous system are unclear. Here, the authors show that fibrinogen is a regulator of the adult neural stem/progenitor cell switch from neurogenesis to astrogenesis in a model of stroke
format	article
author	Lauriane Pous Sachin S. Deshpande Suvra Nath Szilvia Mezey Subash C. Malik Sebastian Schildge Christian Bohrer Könül Topp Dietmar Pfeifer Francisco Fernández-Klett Soroush Doostkam Dennis K. Galanakis Verdon Taylor Katerina Akassoglou Christian Schachtrup
author_facet	Lauriane Pous Sachin S. Deshpande Suvra Nath Szilvia Mezey Subash C. Malik Sebastian Schildge Christian Bohrer Könül Topp Dietmar Pfeifer Francisco Fernández-Klett Soroush Doostkam Dennis K. Galanakis Verdon Taylor Katerina Akassoglou Christian Schachtrup
author_sort	Lauriane Pous
title	Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling
title_short	Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling
title_full	Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling
title_fullStr	Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling
title_full_unstemmed	Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling
title_sort	fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via bmp signaling
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/f3d973f0777646bfaf11ff6400d0b81e
work_keys_str_mv	AT laurianepous fibrinogeninducesneuralstemcelldifferentiationintoastrocytesinthesubventricularzoneviabmpsignaling AT sachinsdeshpande fibrinogeninducesneuralstemcelldifferentiationintoastrocytesinthesubventricularzoneviabmpsignaling AT suvranath fibrinogeninducesneuralstemcelldifferentiationintoastrocytesinthesubventricularzoneviabmpsignaling AT szilviamezey fibrinogeninducesneuralstemcelldifferentiationintoastrocytesinthesubventricularzoneviabmpsignaling AT subashcmalik fibrinogeninducesneuralstemcelldifferentiationintoastrocytesinthesubventricularzoneviabmpsignaling AT sebastianschildge fibrinogeninducesneuralstemcelldifferentiationintoastrocytesinthesubventricularzoneviabmpsignaling AT christianbohrer fibrinogeninducesneuralstemcelldifferentiationintoastrocytesinthesubventricularzoneviabmpsignaling AT konultopp fibrinogeninducesneuralstemcelldifferentiationintoastrocytesinthesubventricularzoneviabmpsignaling AT dietmarpfeifer fibrinogeninducesneuralstemcelldifferentiationintoastrocytesinthesubventricularzoneviabmpsignaling AT franciscofernandezklett fibrinogeninducesneuralstemcelldifferentiationintoastrocytesinthesubventricularzoneviabmpsignaling AT soroushdoostkam fibrinogeninducesneuralstemcelldifferentiationintoastrocytesinthesubventricularzoneviabmpsignaling AT denniskgalanakis fibrinogeninducesneuralstemcelldifferentiationintoastrocytesinthesubventricularzoneviabmpsignaling AT verdontaylor fibrinogeninducesneuralstemcelldifferentiationintoastrocytesinthesubventricularzoneviabmpsignaling AT katerinaakassoglou fibrinogeninducesneuralstemcelldifferentiationintoastrocytesinthesubventricularzoneviabmpsignaling AT christianschachtrup fibrinogeninducesneuralstemcelldifferentiationintoastrocytesinthesubventricularzoneviabmpsignaling
_version_	1718380407343284224

Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling

Ejemplares similares